dcxr
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  • Official Full Name
  • dicarbonyl/L-xylulose reductase
  • Background
  • The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • DCXR; dicarbonyl/L-xylulose reductase; L-xylulose reductase; DCR; KIDCR; SDR20C1; short chain dehydrogenase/reductase family 20C; member 1; carbonyl reductase 2; carbonyl reductase II; sperm surface protein P34H; kidney dicarbonyl reductase; short chain d
Cat.#:DCXR-2424HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DCXR Protein, GST-tagged
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Cat.#:DCXR-11874HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DCXR, GST-tagged
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Cat.#:DCXR-128HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DCXR protein, His-tagged
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Cat.#:DCXR-26175THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DCXR, His-tagged
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Cat.#:DCXR-2726HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Dicarbonyl/L-xylulose Reductase, His-tagged
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Cat.#:DCXR-490HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DCXR, His tagged
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Cat.#:DCXR-1806RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat DCXR Protein
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Cat.#:DCXR-5798CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken DCXR
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Cat.#:DCXR-2390ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish DCXR
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Cat.#:DCXR-7030HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human DCXR 293 Cell Lysate
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Involved Pathway

DCXR involved in several pathways and played different roles in them. We selected most pathways DCXR participated on our site, such as Pentose and glucuronate interconversions, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with DCXR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Pentose and glucuronate interconversions
UGT1A7; ALDH3A2A; ALDH3A2; UGP2B; AKR1B1L; UGT1A6A; UGT1A6; UGT2A2; RPE; AKR1B10
Metabolic pathways
GGT5; AGL; SPHK1; PAH; NDUFS2; SDHDA; MAN2A1; GAD1B; MCAT; HSD17B6

Protein Function

DCXR has several biochemical functions, for example, L-xylulose reductase (NADP+) activity, oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor. Some of the functions are cooperated with other proteins, some of the functions could acted by DCXR itself. We selected most functions DCXR had, and list some proteins which have the same functions with DCXR. You can find most of the proteins on our site.
Function
Related Protein
Function L-xylulose reductase (NADP+) activity
Related Protein DCXR
Function oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
Related Protein AKR1C4; DCXR; AKR1C3; NDUFS7; DHRS4; CBR1; AKR1C6; AKR1C21; AKR1C2

Interacting Protein

DCXR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DCXR here. Most of them are supplied by our site. Hope this information will be useful for your research of DCXR.
DMWD; GSTK1; TRAF6; CRADD; ssrna_ac