| Official Full Name | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| Background | This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif;Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving;alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome;and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be;involved in embryogenesis, spermatogenesis, and cellular growth and division. The nucleolar protein encoded by this;gene interacts in a hormone-dependent manner with nuclear receptors, and represses their transcriptional activity.;Alternative splice variants that encode different isoforms have been found for this gene. |
| Synonyms | DDX54; DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; ATP-dependent RNA helicase DDX54; APR 5; DP97; MGC2835; DEAD box protein 54; DEAD box helicase 97 KDa; DEAD box RNA helicase 97 kDa; ATP-dependent RNA helicase DP97 |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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DDX54 involved in several pathways and played different roles in them. We selected most pathways DDX54 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DDX54 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
DDX54 has several biochemical functions, for example, ATP binding, ATP-dependent RNA helicase activity, estrogen receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX54 itself. We selected most functions DDX54 had, and list some proteins which have the same functions with DDX54. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | IRAK4; FIGN; SMC6; DDR1; CLK2; CHEK2; UBA5; PAPSS2B; NAIP6; DNAH14 |
| ATP-dependent RNA helicase activity | DDX41; DDX42; DDX3; DDX25; EIF4A1; DDX39AA; DDX51; TDRD12; DDX20; DHX33 |
| estrogen receptor binding | PPARG; PADI2; MMS19; NCOA1; NRIP1; NKX3; TMEM38A; FOXL2; CNOT1; HSD17B10 |
| poly(A) RNA binding | ISG20L2; MANF; CDK11B; EIF2S1; THUMPD1; SRSF2; APEX1; MRPL11; TWF2; SAMD4B |
| receptor binding | STOML2; RCHY1; HACL1; NPPB; GLA; P2RX4; MPV17L; PVRL1B; CCL2; GRP |
| transcription corepressor activity | NEUROD2; MECP2; RELB; TMEM38A; NCOR2; JAZF1; SFMBT1; CIR1; TAF9B; SAP30 |
DDX54 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX54 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX54.
ESR1; LYAR; POLR2G; TMED9; SEMA4A; ssrna_ug; MNDA; IFI16; FAM83H; Tnpo1; SRPK3
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