dedd
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  • Official Full Name
  • death effector domain containing
  • Background
  • This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.
  • Synonyms
  • DEDD; death effector domain containing; death effector domain-containing protein; CASP8IP1; DEDD1; DEFT; FLDED1; KE05; Death effector domain containing protein; Death effector domain containing testicular molecule; DEDD 1; DEDPro 1; DEDPro1; FLDED 1; KE 05; OTTHUMP00000031822; FLDED-1; OTTHUMP00000031821; death effector domain-containing testicular molecule
Cat.#:DEDD-2513HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DEDD Protein, GST-tagged
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Cat.#:DEDD-538HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DEDD Protein, His-tagged
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Cat.#:DEDD-539HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DEDD Protein, His-tagged
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Cat.#:DEDD-7245HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DEDD, His-tagged
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Cat.#:DEDD-1827RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat DEDD Protein
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Cat.#:DEDD-1225RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey DEDD Protein, His-tagged
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Cat.#:DEDD-750ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish DEDD
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Cat.#:DEDD-6995HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human DEDD 293 Cell Lysate
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Cat.#:DEDD-6996HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human DEDD 293 Cell Lysate
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Protein Function

DEDD has several biochemical functions, for example, DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DEDD itself. We selected most functions DEDD had, and list some proteins which have the same functions with DEDD. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein NAT14; HIST2H3C; HOXC12A; SP110; HOXB8B; ZNF573; MAP1S; HOXB1A; GATA4; NKX2-5
Function protein binding
Related Protein ID2; LMO4; CD300LG; HEMK1; SH3RF1; SF3A3; SERPINB5; FAAH; KRTAP12-2; IGF2BP3

Interacting Protein

DEDD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DEDD here. Most of them are supplied by our site. Hope this information will be useful for your research of DEDD.
APLP2; C7orf28A; PAM; ARID4A; ATP6V1E1; KHK; SMAD3; TCEAL5; RSRC2; ABCA9; USP7; LTV1; SERPINI1; RANBP3; CCDC59; USP22; SHMT1; BATF2