DNAJC19

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DNAJC19

Official Full Name DnaJ (Hsp40) homolog, subfamily C, member 19
Background The protein encoded by this gene is thought to be part of a complex involved in the ATP-dependent transport of transit peptide-containing proteins from the inner cell membrane to the mitochondrial matrix. Defects in this gene are a cause of 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA). Several transcript variants, some protein-coding and some not, have been found for this gene.
Synonyms DNAJC19; DnaJ (Hsp40) homolog, subfamily C, member 19; mitochondrial import inner membrane translocase subunit TIM14; Pam18; Tim14; TIMM14; DnaJ homolog subfamily C member 19; homolog of yeast TIM14; TIM 14; TIMM 14; translocase of the inner mitochondrial membrane 14
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Dnajc19-2606M Recombinant Mouse Dnajc19 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human DNAJC19-12079H Recombinant Human DNAJC19, GST-tagged E.coli GST
    Human DNAJC19-26773TH Recombinant Human DNAJC19, His-tagged E.coli His
    Human DNAJC19-2756H Recombinant Human DNAJC19 Protein, His-tagged E.coli His
    Human DNAJC19-3405H Recombinant Human DNAJC19, His-tagged E.coli His
    Human DNAJC19-6875HCL Recombinant Human DNAJC19 293 Cell Lysate HEK293 N/A
    Rhesus Macaque DNAJC19-1290R Recombinant Rhesus monkey DNAJC19 Protein, His-tagged Mammalian Cell His
    Zebrafish DNAJC19-11024Z Recombinant Zebrafish DNAJC19 Mammalian Cell His

    DNAJC19 involved in several pathways and played different roles in them. We selected most pathways DNAJC19 participated on our site, such as Metabolism of proteins, Mitochondrial protein import, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNAJC19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism of proteins ARSI; SCFD1; NSMCE4A; ST8SIA2; KCNA3; TOMM22; CTSH; CBX4; TOMM20; PDIA6
    Mitochondrial protein import SLC25A12; TIMM8A; TIMM23; TIMM22; TOMM7; HSCB; COX17; MTX1; GRPEL2; TOMM70A

    DNAJC19 has several biochemical functions, for example, ATPase activator activity, protein binding, contributes_to protein transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DNAJC19 itself. We selected most functions DNAJC19 had, and list some proteins which have the same functions with DNAJC19. You can find most of the proteins on our site.

    Function Related Protein
    ATPase activator activity AHSA1; DNAJB1; DNAJC19; DNAJC24; DNAJC10; RAB4A; TOR1AIP2; AHSA1L; DNAJC15; ATP1B2
    protein binding GFPT2; LARP7; SETD7; PLEKHN1; GLMN; TMEM67; CALM2; PDLIM2; ZNF230; TICAM1
    contributes_to protein transporter activity DNAJC15; VPS29; DNAJC19; TOMM5

    DNAJC19 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNAJC19 here. Most of them are supplied by our site. Hope this information will be useful for your research of DNAJC19.

    TFAP2A; Cct2; FBXO31

    Taboada, X; Hermida, M; et al. Fine Mapping and Evolution of the Major Sex Determining Region in Turbot (Scophthalmus maximus). G3-GENES GENOMES GENETICS 4:1871-1880(2014).
    Richter-Dennerlein, R; Korwitz, A; et al. DNAJC19, a Mitochondrial Cochaperone Associated with Cardiomyopathy, Forms a Complex with Prohibitins to Regulate Cardiolipin Remodeling. CELL METABOLISM 20:158-171(2014).

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