dnajc2
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  • Official Full Name
  • DnaJ (Hsp40) homolog, subfamily C, member 2
  • Background
  • M-phase phosphoprotein 11 is a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. MPP11 is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chape
  • Synonyms
  • DNAJC2; DnaJ (Hsp40) homolog, subfamily C, member 2; ZRF1, zuotin related factor 1; dnaJ homolog subfamily C member 2; MPHOSPH11; MPP11; ZUO1; zuotin; zuotin related factor 1; zuotin-related factor 1; M-phase phosphoprotein 11; ZRF1
Cat.#:DNAJC2-2388HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human DNAJC2 Protein, MYC/DDK-tagged
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Cat.#:DNAJC2-26774THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DNAJC2, His-tagged
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Cat.#:DNAJC2-4707MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse DNAJC2 Protein
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Cat.#:Dnajc2-7943MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Dnajc2 protein, His & T7-tagged
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Cat.#:DNAJC2-1908RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat DNAJC2 Protein
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Cat.#:DNAJC2-468CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus DNAJC2 Protein, His-tagged
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Cat.#:DNAJC2-1291RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey DNAJC2 Protein, His-tagged
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Cat.#:DNAJC2-4262CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken DNAJC2
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Cat.#:DNAJC2-12077ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish DNAJC2
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Involved Pathway

DNAJC2 involved in several pathways and played different roles in them. We selected most pathways DNAJC2 participated on our site, such as Cellular response to heat stress, Cellular responses to stress, Regulation of HSF1-mediated heat shock response, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNAJC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cellular response to heat stress
HSBP1; DNAJC7; KIAA1967; NUP50; HSPH1; ST13; HSPA14; HSBP1A; MAPKAPK2B; EEF1A1
Cellular responses to stress
GABARAP; LAMTOR1; RBBP7; RRAGB; HIST1H1C; HIST1H1B; EGLN1B; HSPA7; EPAS1B; H3F3D
Regulation of HSF1-mediated heat shock response
HSPA13; ST13; HSPH1; C11orf73; DNAJC7; BAG3; KIAA1967; DNAJB6; HSPA14; BAG5

Protein Function

DNAJC2 has several biochemical functions, for example, DNA binding, Hsp70 protein binding, chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNAJC2 itself. We selected most functions DNAJC2 had, and list some proteins which have the same functions with DNAJC2. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein PAX7B; KDM5A; ZNF34; ILF3; HMGA1B; NTNG1; FOXO4; LIG3; HOXB1; ARID2
Function Hsp70 protein binding
Related Protein METTL21A; RPS3; DNAJB2; DNAJA1; C11orf73; FAM119A; BAG6; DNAJB1; RNF207; ST13
Function chromatin binding
Related Protein DNMT1; ARID5A; HDAC5; TGIF1; LMO2; HMGB2; HCFC1; ENY2; PDX1; KDM5A
Function histone binding
Related Protein ANP32E; CHD2; PHF21B; ANP32B; BRD1; HIST1H4L; USP49; TBL1XR1; HINFP; HIST1H4H
Function poly(A) RNA binding
Related Protein PTRH1; FASTKD3; RPL29; EIF4E2; XRN1; RPL8; CISD2; CLK3; METAP2; USO1
Function ubiquitin binding
Related Protein SMAD3; UBE2NB; SQSTM1; OTUB1B; MARK4; VPS36; CXCR4; FAN1; UBXN2A; USP5

Interacting Protein

DNAJC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNAJC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DNAJC2.
SGTB; Hspa14