dnajc24
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  • Official Full Name
  • DnaJ (Hsp40) homolog, subfamily C, member 24
  • Background
  • Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM;130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation;and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in;synthesis of diphthamide in EEF2 (Liu et al., 2004 (PubMed 15485916)).
  • Synonyms
  • DNAJC24; DnaJ (Hsp40) homolog, subfamily C, member 24; DPH4, DPH4 homolog (JJJ3, S. cerevisiae) , DPH4, JJJ3 homolog (S. cerevisiae) , ZCSL3, zinc finger, CSL type containing 3; dnaJ homolog subfamily C member 24; JJJ3; 1700030A21Rik; DPH4, JJJ3 homolo
Cat.#:DNAJC24-2758HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DNAJC24 Protein, GST-tagged
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Cat.#:DNAJC24-12081HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DNAJC24, GST-tagged
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Cat.#:DNAJC24-7600HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DNAJC24, His-tagged
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Cat.#:DNAJC24-1293RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey DNAJC24 Protein, His-tagged
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Cat.#:DNAJC24-4107CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken DNAJC24
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Cat.#:DNAJC24-10756ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish DNAJC24
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Cat.#:DNAJC24-6874HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human DNAJC24 293 Cell Lysate
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Involved Pathway

DNAJC24 involved in several pathways and played different roles in them. We selected most pathways DNAJC24 participated on our site, such as Gamma carboxylation, hypusine formation and arylsulfatase activation, Metabolism of proteins, Post-translational protein modification, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNAJC24 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Gamma carboxylation, hypusine formation and arylsulfatase activation
SUMF2; ARSK; ARSF; PROZ; ARSI; ARSD; DPH2; FURINA; DPH5; WDR85
Metabolism of proteins
ST6GAL2B; PROZ; PAPPA2; FBXW5; TRAPPC10; DDX11; HSCB; SENP5; APEH; SLC34A2A
Post-translational protein modification
MCFD2; SMC6; SEC23IP; TRAPPC9; TRAPPC1; THSD1; GNE; SENP5; ADAMTSL5; ARSE
Synthesis of diphthamide-EEF2
DPH2; DPH1; ATPBD4; DPH3; DNAJC24; WDR85; DPH5; OTOP2

Protein Function

DNAJC24 has several biochemical functions, for example, ATPase activator activity, ferrous iron binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNAJC24 itself. We selected most functions DNAJC24 had, and list some proteins which have the same functions with DNAJC24. You can find most of the proteins on our site.
Function
Related Protein
Function ATPase activator activity
Related Protein DNAJC19; ATP1B1; ATP1B3; TOR1AIP2; AHSA1; MYBPC3; TOR1AIP1; DNAJC10; DNAJB1; AHSA1L
Function ferrous iron binding
Related Protein ISCUB; SERPINB1A; FTO; UROD; BCO1; TRR1; TH; TET2; ALKBH2; FECH
Function zinc ion binding
Related Protein RNF41; SCEL; ING2; ZNF3; LIN28B; ADA; DTX2; BTR18; TK1; ZCCHC4