|Official Full Name||DnaJ (Hsp40) homolog, subfamily C, member 24|
|Background||Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM;130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation;and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in;synthesis of diphthamide in EEF2 (Liu et al., 2004 (PubMed 15485916)).|
|Synonyms||DNAJC24; DnaJ (Hsp40) homolog, subfamily C, member 24; DPH4, DPH4 homolog (JJJ3, S. cerevisiae) , DPH4, JJJ3 homolog (S. cerevisiae) , ZCSL3, zinc finger, CSL type containing 3; dnaJ homolog subfamily C member 24; JJJ3; 1700030A21Rik; DPH4, JJJ3 homolo|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
DNAJC24 involved in several pathways and played different roles in them. We selected most pathways DNAJC24 participated on our site, such as Gamma carboxylation, hypusine formation and arylsulfatase activation, Metabolism of proteins, Post-translational protein modification, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNAJC24 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Gamma carboxylation, hypusine formation and arylsulfatase activation||DPH2; DPH1; DPH3; FURINA; DNAJC24; PROCA; FURINB; ARSE; OTOP2; EIF5A2|
|Metabolism of proteins||CEACAM21; TIMM23; ARL2; PFDN4; ADAMTSL5; ST6GALNAC1.2; PFDN2; PIGK; IGFBP1B; ARSE|
|Post-translational protein modification||SEC23IP; GALNT13; EIF5A2; STT3A; TRAPPC4; GALNT5; ARSH; RNF2; PHC2; GNE|
|Synthesis of diphthamide-EEF2||ATPBD4; DPH1; OTOP2; WDR85; DPH3; DPH5; DPH2; DNAJC24|
DNAJC24 has several biochemical functions, for example, ATPase activator activity, ferrous iron binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNAJC24 itself. We selected most functions DNAJC24 had, and list some proteins which have the same functions with DNAJC24. You can find most of the proteins on our site.
|ATPase activator activity||DNAJC15; TOR1AIP1; AHSA2; MYBPC3; DNAJC24; ATP1B1; AHSA1L; DNAJB1; RAB4A; AHSA1|
|ferrous iron binding||TRR1; ALKBH3; BCO1; DNAJC24; UROD; TET2; PLOD1; HAAO; SERPINB1A; ISCA1|
|zinc ion binding||MMP19; GM3258; ANPEP; PJA1; RXRAB; SPG7; TGFB1I1; TRIM47; UQCRC2B; APEX2|
DNAJC24 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNAJC24 here. Most of them are supplied by our site. Hope this information will be useful for your research of DNAJC24.