dnajc7
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  • Official Full Name
  • DnaJ (Hsp40) homolog, subfamily C, member 7
  • Background
  • This gene encodes a member of the DNAJ heat shock protein 40 family of proteins that is characterized by two N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. This protein binds the chaperone proteins heat shock proteins 70 and 90 in an ATP-dependent manner and may function as a co-chaperone. Pseudogenes of this gene are found on chromosomes 1 and 6. Alternate splicing results in multiple transcript variants.
  • Synonyms
  • DNAJC7; DnaJ (Hsp40) homolog, subfamily C, member 7; TTC2; dnaJ homolog subfamily C member 7; TPR2; Tetratricopeptide repeat protein 2; TPR repeat protein 2; tetratricopeptide repeat domain 2; DJ11; DJC7
Cat.#:DNAJC7-2768HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DNAJC7 Protein, GST-tagged
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Cat.#:DNAJC7-12090HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DNAJC7, GST-tagged
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Cat.#:DNAJC7-1300RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey DNAJC7 Protein, His-tagged
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Cat.#:DNAJC7-3148CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken DNAJC7
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Cat.#:DNAJC7-12480ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish DNAJC7
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Cat.#:DNAJC7-6870HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human DNAJC7 293 Cell Lysate
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Involved Pathway

DNAJC7 involved in several pathways and played different roles in them. We selected most pathways DNAJC7 participated on our site, such as Cellular response to heat stress, Cellular responses to stress, Regulation of HSF1-mediated heat shock response, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNAJC7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cellular response to heat stress
RPS19BP1; ST13; DPF1; HSBP1; BAG3; NUPL2; HSPH1; C11orf73; HSBP1A; NUP35
Cellular responses to stress
CDKN2B; RBB4L; HSBP1A; ST13; LC3; H3F3B.1; HIST2H3C; SUZ12; WDR45L; CDKN2C
Regulation of HSF1-mediated heat shock response
HSPA13; HSPA14; C11orf73; HSPH1; HSPA12B; BAG3; BAG5; DNAJC7; RPS19BP1; KIAA1967

Protein Function

DNAJC7 has several biochemical functions, for example, heat shock protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNAJC7 itself. We selected most functions DNAJC7 had, and list some proteins which have the same functions with DNAJC7. You can find most of the proteins on our site.
Function
Related Protein
Function heat shock protein binding
Related Protein HDAC2; HSPA1A; HSPA8; DNAJA4; PPID; PPP5C; DNAJA2; PACRG; EEF1D; APAF1
Function protein binding
Related Protein COPG; TIMM9; PSMA7; TRIM24; SOCS7; UBE2L3; RPP30; YIPF2; ELAVL2; IL13RA1

Interacting Protein

DNAJC7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNAJC7 here. Most of them are supplied by our site. Hope this information will be useful for your research of DNAJC7.
BAG2; vif; BAG4; a8k1f4_human; GNB5; HSPA1L; PSMD2; TAB1; ATG2A; GNB2; MAP3K3; SMAD9; SMAD2; MKNK1; DISC1