dok4
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  • Official Full Name
  • docking protein 4
  • Background
  • Docking protein 4 is a protein that in humans is encoded by the DOK4 gene.
  • Synonyms
  • DOK4; docking protein 4; FLJ10488; IRS5; IRS-5; insulin receptor substrate 5; downstream of tyrosine kinase 4
Cat.#:DOK4-2812HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DOK4 Protein, GST-tagged
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Cat.#:DOK4-12129HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DOK4, GST-tagged
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Cat.#:DOK4-498HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human docking protein 4, His-tagged
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Cat.#:DOK4-5099HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DOK4, His-tagged
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Cat.#:DOK4-4763MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse DOK4 Protein
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Cat.#:DOK4-1311RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey DOK4 Protein, His-tagged
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Cat.#:DOK4-6846HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human DOK4 293 Cell Lysate
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Involved Pathway

DOK4 involved in several pathways and played different roles in them. We selected most pathways DOK4 participated on our site, such as Signaling events regulated by Ret tyrosine kinase, which may be useful for your reference. Also, other proteins which involved in the same pathway with DOK4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Signaling events regulated by Ret tyrosine kinase
DOK4; DOK6; GFRA1; PDLIM7; DOK5; GDNF

Protein Function

DOK4 has several biochemical functions, for example, insulin receptor binding, protein binding, receptor signaling protein activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DOK4 itself. We selected most functions DOK4 had, and list some proteins which have the same functions with DOK4. You can find most of the proteins on our site.
Function
Related Protein
Function insulin receptor binding
Related Protein PTPN1; SNX4; DOK7; DOK5; INS2; LMBRD1; SNX1; SHC1; SLC2A2; IRS2
Function protein binding
Related Protein CUL1; CDK20; NSUN4; MNAT1; UBXN8; RAP1A; SF3B4; SMARCA2; ARVCF; RNF213
Function receptor signaling protein activity
Related Protein TGFBR1; IL1RL1; cgr2b; ADCYAP1; RGS14; ARF1; RAF1A; ARAF; CD3E; CD19

Interacting Protein

DOK4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DOK4 here. Most of them are supplied by our site. Hope this information will be useful for your research of DOK4.
OPRM1; DOK3; CCM2; STAT2; PTK2; EGFR; ERBB2; LIX1; OLIG1; RBP7

DOK4 Related Articles

Al Olaby, RR; Cocquerel, L; et al. Identification of a Novel Drug Lead That Inhibits HCV Infection and Cell-to-Cell Transmission by Targeting the HCV E2 Glycoprotein. PLOS ONE 9:-(2014).
Saravanan, S; Pandikumar, P; et al. In Vivo and In Vitro Immunomodulatory Potential of Swertiamarin Isolated from Enicostema axillare (Lam.) A. Raynal That Acts as an Anti-inflammatory Agent. INFLAMMATION 37:1374-1388(2014).