|Official Full Name||docking protein 7|
|Background||The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]|
|Synonyms||DOK7; docking protein 7; CMS1B; C4orf25; protein Dok-7; downstream of tyrosine kinase 7;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
DOK7 involved in several pathways and played different roles in them. We selected most pathways DOK7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DOK7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
DOK7 has several biochemical functions, for example, insulin receptor binding, lipid binding, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DOK7 itself. We selected most functions DOK7 had, and list some proteins which have the same functions with DOK7. You can find most of the proteins on our site.
|insulin receptor binding||DOK5; PTPN1; PHIP; FRS2; DOK7; SHC1; INS1; GRB10; SLC2A2; IGF1R|
|lipid binding||YBX2; FFAR1; STARD7; APOE; PCYT1A; ATP5G3; O3far1; ACBD5A; LPAR2; S1PR4|
|protein kinase binding||TOM1L1; TRAF6; GCET2; JTB; TENC1; SV2A; PLCG1; CCNB3; DVL1; DPYSL2|
DOK7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DOK7 here. Most of them are supplied by our site. Hope this information will be useful for your research of DOK7.
mpzl1; CRK; APPL1; ypel3; EFHC1; GABARAPL2