Recombinant Human DOK7 Protein, GST-tagged

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Recombinant Human DOK7 Protein, GST-tagged

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Cat.No. : DOK7-2816H
Product Overview : Human DOK7 full-length ORF (BAC11367.1, 1 a.a. - 298 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 57 kDa
AA Sequence : MVGASRPPPK PLRPRQLQEV GRQSSSDSGI ATGSHSSYSS SLSSYAGSSL DVWRATDELG SLLSLPAAGA PEPSLCTCLP GTVEYQVPTS LRAHYDTPRS LCLAPRDHSP PSQGSPGNSA ARDSGGQTSA GCPSGWLGTR RRGLVMEAPQ DSEATLPGPA PGEPWEAGGP HAGPPPAFFS ACPVCGGLKG AAASAPGPAT AHSGSPGPVA VDSPGPERPR GESPTYVNIP VSPSSRKQLH YMGLELQEAS EGVRGAGASL YAQIDIMATE TAHRVGVRHA RAREEQLSEL EQRKAAPQ
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : DOK7 docking protein 7 [ Homo sapiens ]
Official Symbol : DOK7
Synonyms : DOK7; docking protein 7; C4orf25, chromosome 4 open reading frame 25; protein Dok-7; Dok 7; FLJ33718; FLJ39137; downstream of tyrosine kinase 7; CMS1B; C4orf25; FLJ90556;
Gene ID : 285489
mRNA Refseq : NM_001164673
Protein Refseq : NP_001158145
MIM : 610285
UniProt ID : Q18PE1

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