dram1
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  • Official Full Name
  • DNA-damage regulated autophagy modulator 1
  • Background
  • This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4.
  • Synonyms
  • DRAM1; DNA-damage regulated autophagy modulator 1; DNA damage-regulated autophagy modulator protein 1; damage regulated autophagy modulator; DRAM; FLJ11259; damage-regulated autophagy modulator
Cat.#:DRAM1-4818MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse DRAM1 Protein
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Cat.#:DRAM1-1327RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey DRAM1 Protein, His-tagged
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Cat.#:DRAM1-1563ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish DRAM1
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Cat.#:DRAM1-235HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human DRAM1 lysate
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Protein Function

DRAM1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DRAM1 itself. We selected most functions DRAM1 had, and list some proteins which have the same functions with DRAM1. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein ROBO2; FOXH1; NUS1; SLBP; USP12; TSC22D1; CPSF6; NASP; Fert2; SV2B

Interacting Protein

DRAM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DRAM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DRAM1.
C1orf21

DRAM1 Related Articles

Guan, JJ; Zhang, XD; et al. DRAM1 regulates apoptosis through increasing protein levels and lysosomal localization of BAX. CELL DEATH & DISEASE 6:-(2015).
Yu, MQ; Jiang, YG; et al. DRAM1 Protects Neuroblastoma Cells from Oxygen-Glucose Deprivation/Reperfusion-Induced Injury via Autophagy. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 15:19253-19264(2014).