DTNA
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Official Full Name
dystrobrevin, alpha
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Overview
The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. -
Synonyms
DTNA; dystrobrevin, alpha; dystrobrevin alpha; D18S892E; DRP3; DTN; DTN 1; DTN 2; DTN 3; dystrophin related protein 3; Alpha-dystrobrevin; DTN-A; DTNA_HUMAN; Dystrophin-related protein 3; FLJ96209; LVNC1; OTTHUMP00000163151; OTTHUMP00000163152; OTTHUMP00000163153; OTTHUMP00000163154; OTTHUMP00000163155; OTTHUMP00000245175; OTTHUMP00000245176; OTTHUMP00000245177; OTTHUMP00000245178;
- Recombinant Proteins
- Cell & Tissue Lysates
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- Myc
- DDK
- N/A
- N
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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| Human | DTNA-2899H | Recombinant Human DTNA Protein, GST-tagged | Wheat Germ | GST |
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| Human | DTNA-6799HCL | Recombinant Human DTNA 293 Cell Lysate | HEK293 | N/A |
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| Human | DTNA-6800HCL | Recombinant Human DTNA 293 Cell Lysate | HEK293 | N/A |
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| Human | DTNA-4059HF | Recombinant Full Length Human DTNA Protein, GST-tagged | In Vitro Cell Free System | GST | 371 amino acids |
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| Human | DTNA-1391H | Recombinant Human DTNA Protein, His-tagged | E.coli | N-His | Met1-Glu288 |
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| Human | DTNA-6227H | Recombinant Human DTNA Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK |
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| Human | DTNA-546H | Recombinant Human DTNA Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK |
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| Mouse | Dtna-2670M | Recombinant Mouse Dtna Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
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| Zebrafish | DTNA-5077Z | Recombinant Zebrafish DTNA | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- DTNA Related Articles
DTNA involved in several pathways and played different roles in them. We selected most pathways DTNA participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DTNA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
DTNA has several biochemical functions, for example, PDZ domain binding, protein binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DTNA itself. We selected most functions DTNA had, and list some proteins which have the same functions with DTNA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| PDZ domain binding | PTEN;ADAM17;PARK2;ARHGAP29;ACOX1;PTENB;DLG4;CIT;SRR |
| protein binding | TUSC2;SLC3A1;GSE1;RABAC1;GAS6;COX4I2;EPHB6;FKBPL;CDK1 |
| zinc ion binding | RNF145B;CREBBP;PGLYRP6;BRF1B;USP20;CUL9;CA2;CAR3;NEIL3 |
DTNA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DTNA here. Most of them are supplied by our site. Hope this information will be useful for your research of DTNA.
DMD; Sync; SYNM; UTRN; DRP2; MARK2; GFI1B; q7cg01_yerpe; APPL1; CBX1
- Q&As
- Reviews
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