Recombinant Full Length Human DTNA Protein, GST-tagged

• Cat.No.: DTNA-4059HF
• Product Overview: Human DTNA full-length ORF ( AAH05300, 1 a.a. - 371 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 66.55 kDa
• Protein Length: 371 amino acids
• AA Sequence: MIEDSGKRGNTMAERRQLFAEMRAQ DLDRIRLSTYRTACKLRFVQKKCNL HLVDIWNVIEALRENALNNLDPNTE LNVSRLEAVLSTIFYQLNKRMPTTH QIHVEQSISLLLNFLLAAFDPEGHG KISVFAVKMALATLCGGKIMDKLRY IFSMISDSSGVMVYGRYDQFLREVL KLPTAVFEGPSFGYTEQSARSCFSQ QKKVTLNGFLDTLMSDPPPQCLVWL PLLHRLANVENVFHPVECSYCHSES MMGFRYRCQQCHNYQLCQDCFWRGH AGGSHSNQHQMKEYTSWKSPAKKLT NALSKSLSCASSREPLHPMFPDQPE KPLNLAHIVPPRPVTSMNDTLFSHS VPSSGSPFITRSSDGAFGGCV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DTNA dystrobrevin, alpha [ Homo sapiens ]
• Official Symbol: DTNA
• Synonyms: DTNA; dystrobrevin, alpha; dystrobrevin alpha; D18S892E; DRP3; DTN; DTN 1; DTN 2; DTN 3; dystrophin related protein 3; dystrophin-related protein 3; DTN-A; LVNC1; FLJ96209
• Gene ID: 1837
• mRNA Refseq: NM_001128175
• Protein Refseq: NP_001121647
• MIM: 601239
• UniProt ID: Q9Y4J8