EIF2B2 Protein, eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa

EIF2B2

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EIF2B2

Official Full Name eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
Background This gene encodes the beta subunit of eukaryotic initiation factor-2B (EIF2B). EIF2B is involved in protein synthesis and exchanges GDP and GTP for its activation and deactivation.
Synonyms EIF2B2; eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa; eukaryotic translation initiation factor 2B, subunit 2 (beta, 39kD); translation initiation factor eIF-2B subunit beta; EIF 2Bbeta; EIF2B; S20I15; S20III15; eIF-2B GDP-GTP exchang
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human EIF2B2-12354H Recombinant Human EIF2B2, GST-tagged E.coli GST
    Human EIF2B2-1535H Recombinant Human EIF2B2, T7-tagged E.coli T7
    Human EIF2B2-3156H Recombinant Human EIF2B2 Protein, GST-tagged Wheat Germ GST
    Human EIF2B2-334H Recombinant Human EIF2B2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human EIF2B2-540HCL Recombinant Human EIF2B2 cell lysate N/A
    Mouse EIF2B2-5080M Recombinant Mouse EIF2B2 Protein Mammalian Cell His
    Rhesus Macaque EIF2B2-1415R Recombinant Rhesus monkey EIF2B2 Protein, His-tagged Mammalian Cell His
    Chicken EIF2B2-1620C Recombinant Chicken EIF2B2 Mammalian Cell His
    Zebrafish EIF2B2-12158Z Recombinant Zebrafish EIF2B2 Mammalian Cell His

    EIF2B2 involved in several pathways and played different roles in them. We selected most pathways EIF2B2 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF2B2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    RNA transport RANGAP1A; EIF4BA; EIF3H; PHAX; NUP133; EIF3EA; NDC1; PRMT5; SUMO1; MAGOHB

    EIF2B2 has several biochemical functions, for example, ATP binding, GTP binding, NOT S-methyl-5-thioribose-1-phosphate isomerase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF2B2 itself. We selected most functions EIF2B2 had, and list some proteins which have the same functions with EIF2B2. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding NOL9; NIM1K; TEX14; PRPS2; HSPA12B; PTK2AA; PRKAG3; PRKAG2; TARS2; MARK4
    GTP binding RAB1BB; GUCY2E; RSG1; NKIRAS1; ARF1L; GNAO1; RHOG; RAB5B; MFHAS1; LRRK1
    NOT S-methyl-5-thioribose-1-phosphate isomerase activity EIF2B2; EIF2B1; EIF2B4; EIF2B3
    contributes_to guanyl-nucleotide exchange factor activity EIF2B5; LAMTOR1; EIF2B2; HBXIP; EIF2B3; C7orf59; EIF2B4; ALS2; LAMTOR2; EIF2B1
    protein binding PRKCE; SMAD7; FAM53C; GP1BB; SLC30A2; GLA; CD24; CCDC88A; CASP14; HELT
    contributes_to translation initiation factor activity EIF3E; EIF3S10; EIF2B5; EIF3K; EIF3M; EIF3L; EIF3BA; EIF3A; EIF3J; EIF3D

    EIF2B2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF2B2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF2B2.

    CSNK2A2; CCT3; C9orf72; pi3p; Srp72; NSS; RPL10; DCC; EPB41L3

    Hata, Y; Kinoshita, K; et al. An autopsy case of infantile-onset vanishing white matter disease related to an EIF2B2 mutation (V85E) in a hemizygous region. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY 7:3355-3362(2014).
    Unal, O; Ozgen, B; et al. Vanishing White Matter With Hepatomegaly and Hypertriglyceridemia Attacks. JOURNAL OF CHILD NEUROLOGY 28:1509-1512(2013).

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