EIF2B5 Protein, eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa

EIF2B5

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EIF2B5

Official Full Name eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
Background This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Nov 2009]
Synonyms EIF2B5; eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa; CLE; CACH; LVWM; EIF-2B; EIF2Bepsilon; translation initiation factor eIF-2B subunit epsilon; eIF-2B GDP-GTP exchange factor subunit epsilon;
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human EIF2B5-3159H Recombinant Human EIF2B5 Protein, GST-tagged Wheat Germ GST
    Human EIF2B5-6669HCL Recombinant Human EIF2B5 293 Cell Lysate HEK293 N/A
    Mouse EIF2B5-5083M Recombinant Mouse EIF2B5 Protein Mammalian Cell His
    Rat EIF2B5-2049R Recombinant Rat EIF2B5 Protein Mammalian Cell His
    Rhesus Macaque EIF2B5-1417R Recombinant Rhesus monkey EIF2B5 Protein, His-tagged Mammalian Cell His
    Zebrafish EIF2B5-6333Z Recombinant Zebrafish EIF2B5 Mammalian Cell His

    EIF2B5 involved in several pathways and played different roles in them. We selected most pathways EIF2B5 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF2B5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    RNA transport SMN1; ELAC1; RPP25L; NUP93; EIF4A1B; SNUPN; SUMO3B; EIF3D; AAAS; NUP37

    EIF2B5 has several biochemical functions, for example, contributes_to guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF2B5 itself. We selected most functions EIF2B5 had, and list some proteins which have the same functions with EIF2B5. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to guanyl-nucleotide exchange factor activity EIF2B4; ALS2; EIF2B5; HBXIP; LAMTOR1; EIF2B2; LAMTOR2; LAMTOR3; C7orf59; EIF2B1
    guanyl-nucleotide exchange factor activity RASGRP2; P2RY12; RALGDS; GAPVD1; RALGPS2; CHRM4; ARHGEF11; RIC8B; VAV2; PREX1
    protein binding RFPL3; GSTA4; CCDC106; HSD17B12; ZCCHC17; GRB7; EMP2; PRPF6; NAPB; FAS
    contributes_to translation initiation factor activity EIF3D; EIF2B1; EIF3HA; EIF3M; EIF3I; EIF3K; EIF2B3; EIF3S10; EIF3A; EIF3B
    translation initiation factor activity EIF3F; EIF5B; EIF5; EIF4E2; EIF1AX; EIF6; EIF4E2RS1; EIF4E3; EIF4H; EIF4BB
    translation initiation factor binding TBL2; LIN28A; RPS24; EIF2B4; ZNF259; DDX3X; CELF1; EIF3C; EIF3F; EIF3M

    EIF2B5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF2B5 here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF2B5.

    pi3p; NSS

    Yang, S; Zhang, H; et al. Reconstructing the coding and non-coding RNA regulatory networks of miRNAs and mRNAs in breast cancer. GENE 548:6-13(2014).
    Zahoor, I; Hamid, Z; et al. Novel mutations identified in EIF2B5 gene in Kashmiri patients as susceptibility factor for multiple sclerosis. INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS 51:115-120(2014).

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