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EIF2B5

  • Official Full Name

    eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa

  • Overview

    This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Nov 2009]
  • Synonyms

    EIF2B5; eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa; CLE; CACH; LVWM; EIF-2B; EIF2Bepsilon; translation initiation factor eIF-2B subunit epsilon; eIF-2B GDP-GTP exchange factor subunit epsilon;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EIF2B5-3159H Recombinant Human EIF2B5 Protein, GST-tagged Wheat Germ GST
Human EIF2B5-6669HCL Recombinant Human EIF2B5 293 Cell Lysate HEK293 N/A
Human EIF2B5-4546HF Recombinant Full Length Human EIF2B5 Protein, GST-tagged In Vitro Cell Free System GST 721 amino acids
Mouse EIF2B5-5083M Recombinant Mouse EIF2B5 Protein Mammalian Cell His
Mouse EIF2B5-2703M Recombinant Mouse EIF2B5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse EIF2B5-2703M-B Recombinant Mouse EIF2B5 Protein Pre-coupled Magnetic Beads HEK293
Rat EIF2B5-2049R Recombinant Rat EIF2B5 Protein Mammalian Cell His
Rat EIF2B5-1706R Recombinant Rat EIF2B5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat EIF2B5-1706R-B Recombinant Rat EIF2B5 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque EIF2B5-1417R Recombinant Rhesus monkey EIF2B5 Protein, His-tagged Mammalian Cell His
Rhesus Macaque EIF2B5-1241R Recombinant Rhesus Macaque EIF2B5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque EIF2B5-1241R-B Recombinant Rhesus Macaque EIF2B5 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish EIF2B5-6333Z Recombinant Zebrafish EIF2B5 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EIF2B5 Related Articles

EIF2B5 involved in several pathways and played different roles in them. We selected most pathways EIF2B5 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF2B5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RNA transportUPF1;EEF1A1L1;MAGOHB;EIF2B4;PABPC4;NCBP2;EIF3EA;PAIP1;EIF5

EIF2B5 has several biochemical functions, for example, contributes_to guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF2B5 itself. We selected most functions EIF2B5 had, and list some proteins which have the same functions with EIF2B5. You can find most of the proteins on our site.

Function Related Protein
contributes_to guanyl-nucleotide exchange factor activityEIF2B5;EIF2B3;EIF2B2;LAMTOR3;EIF2B1;LAMTOR1;EIF2B4;HBXIP;C7orf59
guanyl-nucleotide exchange factor activityTBXAS1;VAV3B;GCGR;ARHGEF18;SBF1;SH2D3CB;RANGRF;RASGEF1BB;ITSN2A
protein bindingSOX7;TBC1D14;COMMD1;RBM10;PSMD9;DNAJA2;FCRL2;COMMD3;CCNL2
contributes_to translation initiation factor activityEIF3C;EIF3J;EIF3A;EIF3K;EIF3L;EIF3D;EIF3F;EIF3EB;EIF3H
translation initiation factor activityEIF5;EIF4G2;EIF1;EIF2S1;DHX29;EIF4A1;EIF4E2;EIF4EA;EIF4H
translation initiation factor bindingEIF2B5;EIF3BA;CELF1;EIF3F;LIN28A;RPS24;EIF2B4;POLR2GL;ZNF259

EIF2B5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF2B5 here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF2B5.

pi3p; NSS

Yang, S; Zhang, H; et al. Reconstructing the coding and non-coding RNA regulatory networks of miRNAs and mRNAs in breast cancer. GENE 548:6-13(2014).
Zahoor, I; Hamid, Z; et al. Novel mutations identified in EIF2B5 gene in Kashmiri patients as susceptibility factor for multiple sclerosis. INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS 51:115-120(2014).
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