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EIF2C3

  • Official Full Name

    eukaryotic translation initiation factor 2C, 3

  • Overview

    This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded;protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in;short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a tandem cluster of closely;related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript;variants encoding distinct isoforms have been identified for this gene.
  • Synonyms

    EIF2C3; eukaryotic translation initiation factor 2C, 3; protein argonaute-3; 5730550L01Rik; Ago 3; Ago3; AGO3_HUMAN; Argonaute3; eIF 2C 3; eIF-2C 3; eIF2C 3; EIF2C3 protein; Eukaryotic translation initiation factor 2C 3; Eukaryotic translation initiation factor 2C3; FLJ12765; hAgo3; MGC86946; mAgo3; argonaute 3; Piwi/Argonaute family protein meIF2C3; AW048688; C130014L07Rik;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • HEK293
  • In Vitro Cell Free System
  • Insect Cells
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EIF2C3-5174H Recombinant Human EIF2C3 protein(Met1-Ala860), His-tagged Insect Cells N-His Met1-Ala860
Human EIF2C3-3166H Recombinant Human EIF2C3 Protein, GST-tagged Wheat Germ GST
Human EIF2C3-6666HCL Recombinant Human EIF2C3 293 Cell Lysate HEK293 N/A
Human EIF2C3-4571HF Recombinant Full Length Human EIF2C3 Protein, GST-tagged In Vitro Cell Free System GST 626 amino acids
Mouse EIF2C3-5085M Recombinant Mouse EIF2C3 Protein Mammalian Cell His
Mouse EIF2C3-2704M Recombinant Mouse EIF2C3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse EIF2C3-2704M-B Recombinant Mouse EIF2C3 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

EIF2C3 involved in several pathways and played different roles in them. We selected most pathways EIF2C3 participated on our site, such as Gene Expression, Gene Silencing by RNA, Post-transcriptional silencing by small RNAs, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF2C3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Gene ExpressionNFIA;SAP18;ZNF155;TH1L;DNMT3B;EIF4B;HBXIP;GTF3C3;ZNF664
Gene Silencing by RNATSN;EIF2C3;ASZ1;PLD6;FKBP6;TSNAX;BARHL1;PIWIL4;DPY19L2
Post-transcriptional silencing by small RNAsAGO3B;TNRC6B;EIF2C3

EIF2C3 has several biochemical functions, for example, RNA binding, double-stranded RNA binding, miRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF2C3 itself. We selected most functions EIF2C3 had, and list some proteins which have the same functions with EIF2C3. You can find most of the proteins on our site.

Function Related Protein
RNA bindingHNRPK;IFIT14;EIF5A;RPL26;RPLP1;NOVA2;PABPC1L;ARHGEF28;SF3A1
double-stranded RNA bindingOAS1;AGO3;HSP90AB1;SUPV3L1;HMGB1;DDX21;OASL1;EIF4A1;LSM14A
miRNA bindingRBM4;LIN28A;AGO1;AGO4;MEF2C;PNPT1;DICER1;POU5F1;AGO3
nucleic acid bindingZFP865;SRSF7B;ZFP110;CPSF1;RNASEH1;TIGD3;EIF4A1A;ZFP239;PABPC1L
poly(A) RNA bindingTPR;CCDC47;PCSK9;NUDT21;RBM15;DIDO1;TPD52L2;HELZ;RPL8
single-stranded RNA bindingANXA1;CBX8;POLR2GL;AGO3;A1CF;IFIT5;JMJD6;HNRNPA1;DDX58

EIF2C3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF2C3 here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF2C3.

Ago2

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