|Official Full Name||eukaryotic translation initiation factor 3, subunit B|
|Background||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.|
|Synonyms||EIF3B; eukaryotic translation initiation factor 3, subunit B; PRT1; EIF3S9; EIF3-ETA; EIF3-P110; EIF3-P116; eukaryotic translation initiation factor 3 subunit B; hPrt1; eIF-3-eta; eIF3 p110; eIF3 p116; prt1 homolog; eukaryotic translation initiation factor 3 subunit 9; eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa; eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD);|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
EIF3B involved in several pathways and played different roles in them. We selected most pathways EIF3B participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF3B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|RNA transport||SMN1; TPR; UPF3B; EIF2B2; UPF3A; EIF4E2; NUP188; RPP38; NUP153; EIF3HB|
EIF3B has several biochemical functions, for example, RNA binding, nucleic acid binding, nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF3B itself. We selected most functions EIF3B had, and list some proteins which have the same functions with EIF3B. You can find most of the proteins on our site.
|RNA binding||RPL7A; EIF4G2B; YY1; RPL22; NOVA2; HNRNPR; JAKMIP1; SRRM4; HNRNPH3; RPLP2|
|nucleic acid binding||PRDM1A; ZFP287; TDRD9; TDRD12; KLF11B; ZFP639; OSR1; KLF6A; GTF3A; HNRNPA0A|
|nucleotide binding||RBM44; ATP1A1A.2; LOC81691; MAP4K6; DIRAS1A; HNRNPL; HSPA12A; TUBA4L; PANK1A; NIM1|
|protein binding||COX6B2; AKT3; TFIP11; SENP3; IFIT2; RAB27A; OPRK1; EYA3; DDX55; MARCH10|
|contributes_to translation initiation factor activity||EIF3H; EIF3E; EIF2B1; EIF3D; EIF3L; EIF3B; EIF3I; EIF3F; EIF2B5; EIF3EA|
|translation initiation factor activity||EIF4E2RS1; EIF4E1B; EIF1AD; GTPBP1; EIF2A; EIF2S3Y; EIF2D; EIF1; EIF1AY; EIF5B|
|translation initiation factor binding||POLR2D; LARP1; LIN28A; TBL2; TRIM32; EIF3M; POLR2GL; EIF3F; ZNF259; CELF1|
EIF3B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF3B here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF3B.
Eif3a; Eif4a1; Rps6; Eif4e; Eif4g1; Rps6kb1; Eif3i; Ywhae