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EIF3K

  • Official Full Name

    eukaryotic translation initiation factor 3, subunit K

  • Overview

    The 700-kD eukaryotic translation initiation factor-3 (eIF3) is the largest eIF and contains at least 12 subunits,;including EIF2S12. eIF3 plays an essential role in translation by binding directly to the 40S ribosomal subunit and;promoting formation of the 40S preinitiation complex (Mayeur et al., 2003 (PubMed 14519125)).
  • Synonyms

    EIF3K; eukaryotic translation initiation factor 3, subunit K; EIF3S12, eukaryotic translation initiation factor 3, subunit 12; eukaryotic translation initiation factor 3 subunit K; ARG134; HSPC029; M9; PLAC 24; PRO1474; PTD001; eIF-3 p25; eIF-3 p2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Others
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EIF3K-8658H Recombinant Human EIF3K, His-GST tagged Insect Cell His
Human EIF3K-3482H Recombinant Human EIF3K, His-tagged E.coli His
Human EIF3K-27408TH Recombinant Human EIF3K, His-tagged E.coli His
Human EIF3K-3191H Recombinant Human EIF3K Protein, GST-tagged Wheat Germ GST
Human EIF3K-001HCL Recombinant Human EIF3K cell lysate Insect Cell N/A
Human EIF3K-5518H Recombinant Human EIF3K Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human EIF3K-4277HF Recombinant Full Length Human EIF3K Protein, GST-tagged In Vitro Cell Free System GST 218 amino acids
Human EIF3K-4810H Recombinant Human EIF3K protein, GST-tagged E.coli GST 2-218aa
Human EIF3K-2204H Recombinant Human EIF3K protein, His&GST-tagged Insect Cells His/GST Ala2-Gln218
Mouse EIF3K-5100M Recombinant Mouse EIF3K Protein Mammalian Cell His
Mouse Eif3k-2782M Recombinant Mouse Eif3k Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse EIF3K-2713M Recombinant Mouse EIF3K Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse EIF3K-2713M-B Recombinant Mouse EIF3K Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque EIF3K-1425R Recombinant Rhesus monkey EIF3K Protein, His-tagged Mammalian Cell His
Rhesus Macaque EIF3K-1249R-B Recombinant Rhesus Macaque EIF3K Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque EIF3K-1249R Recombinant Rhesus Macaque EIF3K Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish EIF3K-2361Z Recombinant Zebrafish EIF3K Mammalian Cell His
CBCRY12 Eukaryotic translation initiation factor 3 subunit K E.coli N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein

EIF3K involved in several pathways and played different roles in them. We selected most pathways EIF3K participated on our site, such as Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, Cap-dependent Translation Initiation, Eukaryotic Translation Initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF3K were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43SEIF4A2;EIF4A1;EIF4H;EIF3K;EIF4EBP1;EIF4G1;EIF2S1;EIF4EB;EIF1AXA
Cap-dependent Translation InitiationEIF4EBP1;EIF4A1;EIF1AX;EIF4B;EIF1AXA;RPL35;EIF4A2;EIF4H;EIF3K
Eukaryotic Translation InitiationEIF3K;EIF4B;EIF2S3;EIF4A2;EIF4H;EIF4G1;EIF1AX;RPL35;FAUB
Formation of a pool of free 40S subunitsEIF1AX;EIF1AXA;EIF3K;RPL35;FAUB
Formation of the ternary complex, and subsequently, the 43S complexEIF3K;EIF2S1A;EIF2S3;EIF1AXA;EIF1AX;EIF2S1;FAUB
GTP hydrolysis and joining of the 60S ribosomal subunitEIF1AXA;EIF4A2;EIF2S1;EIF3K;RPL35;EIF1AX;EIF5;EIF2S1A;EIF4A1
Gene ExpressionKIAA1456;ZMAT5;FARSB;EIF2B1;DPY19L2;TSN;PCBP2;BARHL1;LAGE3
L13a-mediated translational silencing of Ceruloplasmin expressionEIF1AXA;EIF2S1A;FAUB;EIF2S3;EIF3K;EIF4H;EIF1AX

EIF3K has several biochemical functions, for example, RNA binding, ribosome binding, contributes_to translation initiation factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF3K itself. We selected most functions EIF3K had, and list some proteins which have the same functions with EIF3K. You can find most of the proteins on our site.

Function Related Protein
RNA bindingSMN2;OASL2;LIN28B;BXDC2;EIF4E3;HSP90B1;ZMAT4;RAE1;CNOT8
ribosome bindingETF1B;YTHDF1;SEC61A1;NARG1;EIF3K;CPEB1;OLA1;HSPA5;BAG6
contributes_to translation initiation factor activityEIF3S6IP;EIF3I;EIF2B5;EIF3C;EIF3A;EIF3K;EIF2B1;EIF3F;EIF3EB

EIF3K has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF3K here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF3K.

Eif3a; Ywhae

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