EIF3K Protein, eukaryotic translation initiation factor 3, subunit K


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Official Full Name eukaryotic translation initiation factor 3, subunit K
Background The 700-kD eukaryotic translation initiation factor-3 (eIF3) is the largest eIF and contains at least 12 subunits,;including EIF2S12. eIF3 plays an essential role in translation by binding directly to the 40S ribosomal subunit and;promoting formation of the 40S preinitiation complex (Mayeur et al., 2003 (PubMed 14519125)).
Synonyms EIF3K; eukaryotic translation initiation factor 3, subunit K; EIF3S12, eukaryotic translation initiation factor 3, subunit 12; eukaryotic translation initiation factor 3 subunit K; ARG134; HSPC029; M9; PLAC 24; PRO1474; PTD001; eIF-3 p25; eIF-3 p2
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human EIF3K-001HCL Recombinant Human EIF3K cell lysate Insect Cell N/A
    Human EIF3K-27408TH Recombinant Human EIF3K, His-tagged E.coli His
    Human EIF3K-3191H Recombinant Human EIF3K Protein, GST-tagged Wheat Germ GST
    Human EIF3K-3482H Recombinant Human EIF3K, His-tagged E.coli His
    Human EIF3K-8658H Recombinant Human EIF3K, His-GST tagged Insect Cell His
    Mouse EIF3K-5100M Recombinant Mouse EIF3K Protein Mammalian Cell His
    Rhesus Macaque EIF3K-1425R Recombinant Rhesus monkey EIF3K Protein, His-tagged Mammalian Cell His
    Zebrafish EIF3K-2361Z Recombinant Zebrafish EIF3K Mammalian Cell His
    CBCRY12 Eukaryotic translation initiation factor 3 subunit K E.coli N/A

    EIF3K involved in several pathways and played different roles in them. We selected most pathways EIF3K participated on our site, such as Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, Cap-dependent Translation Initiation, Eukaryotic Translation Initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF3K were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S EIF4E; EIF4H; EIF2S1A; EIF3K; EIF4EBP1; FAUB; EIF2S3; EIF4B; EIF4G1; EIF4EB
    Cap-dependent Translation Initiation EIF4A2; EIF2B1; EIF2S1A; FAUB; EIF2S3; EIF1AX; EIF4EBP1; EIF4A1; EIF5; EIF1AXA
    Eukaryotic Translation Initiation EIF2B1; FAUB; EIF4B; EIF4A2; EIF2S1A; EIF4H; EIF2S1; EIF4EB; RPL35; EIF4G1
    Formation of a pool of free 40S subunits EIF3K; EIF1AX; FAUB; EIF1AXA; RPL35
    Formation of the ternary complex, and subsequently, the 43S complex FAUB; EIF1AXA; EIF3K; EIF2S1; EIF2S1A; EIF1AX; EIF2S3
    GTP hydrolysis and joining of the 60S ribosomal subunit EIF4A2; EIF1AX; EIF3K; RPL35; EIF2S1; EIF5; EIF2S3; EIF4B; EIF4A1; FAUB
    Gene Expression TET2; DGCR8; FARS2; ZNF669; EEF1G; SESN3; SAP30BP; ZNF599; TAF1L; BARHL1
    L13a-mediated translational silencing of Ceruloplasmin expression EIF1AXA; EIF2S3; EIF1AX; EIF2S1A; FAUB; EIF3K; EIF4H

    EIF3K has several biochemical functions, for example, RNA binding, ribosome binding, contributes_to translation initiation factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF3K itself. We selected most functions EIF3K had, and list some proteins which have the same functions with EIF3K. You can find most of the proteins on our site.

    Function Related Protein
    ribosome binding BAG6; EIF2A; WIBG; EIF5A2; NAA16; CPEB1; EIF2S1; EIF5A; SBDS; ETF1B
    contributes_to translation initiation factor activity EIF3I; EIF3E; EIF3G; EIF2B3; EIF3H; EIF2B4; EIF2B1; EIF3HB; EIF2B2; EIF3K

    EIF3K has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF3K here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF3K.

    Eif3a; Ywhae

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