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EIF4B

  • Official Full Name

    eukaryotic translation initiation factor 4B

  • Synonyms

    EIF4B; eukaryotic translation initiation factor 4B; EIF-4B; PRO1843;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EIF4B-27411TH Recombinant Human EIF4B Wheat Germ N/A 611 amino acids
Human EIF4B-3197H Recombinant Human EIF4B Protein, GST-tagged Wheat Germ GST
Human EIF4B-12378H Recombinant Human EIF4B, GST-tagged E.coli GST 1-350a.a.
Human EIF4B-828H-B Recombinant Human EIF4B Protein Pre-coupled Magnetic Beads HEK293
Human EIF4B-1229H Recombinant Human EIF4B Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human EIF4B-4286HF Recombinant Full Length Human EIF4B Protein, GST-tagged In Vitro Cell Free System GST 611 amino acids
Human EIF4B-146HF Recombinant Full Length Human EIF4B Protein In Vitro Cell Free System 611 amino acids
Human EIF4B-828H Recombinant Human EIF4B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human EIF4B-652HFL Recombinant Full Length Human EIF4B Protein, C-Flag-tagged Mammalian cells Flag
Mouse EIF4B-5105M Recombinant Mouse EIF4B Protein Mammalian Cell His
Mouse Eif4b-2786M Recombinant Mouse Eif4b Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse EIF4B-2717M Recombinant Mouse EIF4B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse EIF4B-2717M-B Recombinant Mouse EIF4B Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EIF4B Related Articles
  • EIF4B Related Research Area
  • EIF4B Related Signal Pathway

EIF4B involved in several pathways and played different roles in them. We selected most pathways EIF4B participated on our site, such as Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, Cap-dependent Translation Initiation, Deadenylation of mRNA, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF4B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43SEIF4A1;EIF4EB;FAUB;EIF3K;EIF2S1;EIF2S3;EIF2S1A;EIF1AX;EIF4G1
Cap-dependent Translation InitiationEIF4EBP1;EIF3K;EIF4EB;EIF1AX;EIF2S1A;EIF4H;EIF2B1;EIF4G1;EIF4A2
Deadenylation of mRNAC2orf29;PAIP1;EIF4A1;EIF4B;EIF4G1;EIF4A2;EIF4E;TNKS1BP1;EIF4EB
Deadenylation-dependent mRNA decayDDX6;EIF4A2;EIF4G1;EIF4B;EXOSC8;DCP1B;TNKS1BP1;D1BWG0212E;NT5C3B
Eukaryotic Translation InitiationEIF4G1;EIF4EB;RPL35;FAUB;EIF5;EIF3K;EIF2S1;EIF4A2;EIF4A1
GTP hydrolysis and joining of the 60S ribosomal subunitEIF5;EIF3K;EIF1AX;EIF4B;EIF4H;FAUB;EIF2S1;EIF4A2;EIF2S3
Gene ExpressionEED;ZNF434;DNMT3A;ZNF738;AEBP2;ZFP28;SNAPC4;ZNF454;ZNF263
IGF1R signaling cascadeHBXIP;EIF4B;C7orf59;LAMTOR1;IGF2B;RRAGB;RRAGA

EIF4B has several biochemical functions, for example, RNA binding, nucleotide binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF4B itself. We selected most functions EIF4B had, and list some proteins which have the same functions with EIF4B. You can find most of the proteins on our site.

Function Related Protein
RNA bindingPES;FBL;EIF2C3;TRIM21;PUF60B;Aff2;PABPN1;DDX51;UBR5
nucleotide bindingTTLL9;SEPT5B;ATP2B2;RPS6KA3B;RHOAC;NCBP2;TARDBPL;HSP70;Atp8a2
poly(A) RNA bindingHMGB2;NOP2;GAR1;CSTF2T;CRNKL1;GLTSCR2;NUCKS1;HSP90AB1;RPS8
protein bindingNFKBIB;ZNF41;RPS13;AGBL1;GOLGA1;FAM86C;MEF2A;RBM42;CYC1
translation initiation factor activityEIF2S3Y;EIF5B;EIF4EB;EIF2B5;MCTS1;EIF3S10;EIF4G3;EIF4A2;EIF4A1A

EIF4B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF4B here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF4B.

EIF3A; TINF2; npm_alk; PLK1; CSNK2A1; CAMK2D; RPS6KA1; EIF3H; USP11; Ccdc15; KBTBD7; NELL1

Osman, AM; van Loveren, H; et al. The immunosuppressant tributyltin oxide blocks the mTOR pathway, like rapamycin, albeit by a different mechanism. JOURNAL OF APPLIED TOXICOLOGY 34:1361-1367(2014).
Hernandez, G; Lalioti, V; et al. Identification and characterization of the expression of the translation initiation factor 4A (eIF4A) from Drosophila melanogaster. PROTEOMICS 4:316-326(2004).
von der Haar, T; McCarthy, JEG; et al. Intracellular translation initiation factor levels in Saccharomyces cerevisiae and their role in cap-complex function. MOLECULAR MICROBIOLOGY 46:531-544(2002).
Metz, AM; Wong, KCH; et al. Eukaryotic initiation factor 4B from wheat and Arabidopsis thaliana is a member of a multigene family. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 266:314-321(1999).
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