EIF4B
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Official Full Name
eukaryotic translation initiation factor 4B
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Synonyms
EIF4B; eukaryotic translation initiation factor 4B; EIF-4B; PRO1843;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- EIF4B Related Articles
- EIF4B Related Research Area
- EIF4B Related Signal Pathway
EIF4B involved in several pathways and played different roles in them. We selected most pathways EIF4B participated on our site, such as Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, Cap-dependent Translation Initiation, Deadenylation of mRNA, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF4B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | EIF4A1;EIF4EB;FAUB;EIF3K;EIF2S1;EIF2S3;EIF2S1A;EIF1AX;EIF4G1 |
Cap-dependent Translation Initiation | EIF4EBP1;EIF3K;EIF4EB;EIF1AX;EIF2S1A;EIF4H;EIF2B1;EIF4G1;EIF4A2 |
Deadenylation of mRNA | C2orf29;PAIP1;EIF4A1;EIF4B;EIF4G1;EIF4A2;EIF4E;TNKS1BP1;EIF4EB |
Deadenylation-dependent mRNA decay | DDX6;EIF4A2;EIF4G1;EIF4B;EXOSC8;DCP1B;TNKS1BP1;D1BWG0212E;NT5C3B |
Eukaryotic Translation Initiation | EIF4G1;EIF4EB;RPL35;FAUB;EIF5;EIF3K;EIF2S1;EIF4A2;EIF4A1 |
GTP hydrolysis and joining of the 60S ribosomal subunit | EIF5;EIF3K;EIF1AX;EIF4B;EIF4H;FAUB;EIF2S1;EIF4A2;EIF2S3 |
Gene Expression | EED;ZNF434;DNMT3A;ZNF738;AEBP2;ZFP28;SNAPC4;ZNF454;ZNF263 |
IGF1R signaling cascade | HBXIP;EIF4B;C7orf59;LAMTOR1;IGF2B;RRAGB;RRAGA |
EIF4B has several biochemical functions, for example, RNA binding, nucleotide binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF4B itself. We selected most functions EIF4B had, and list some proteins which have the same functions with EIF4B. You can find most of the proteins on our site.
Function | Related Protein |
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RNA binding | PES;FBL;EIF2C3;TRIM21;PUF60B;Aff2;PABPN1;DDX51;UBR5 |
nucleotide binding | TTLL9;SEPT5B;ATP2B2;RPS6KA3B;RHOAC;NCBP2;TARDBPL;HSP70;Atp8a2 |
poly(A) RNA binding | HMGB2;NOP2;GAR1;CSTF2T;CRNKL1;GLTSCR2;NUCKS1;HSP90AB1;RPS8 |
protein binding | NFKBIB;ZNF41;RPS13;AGBL1;GOLGA1;FAM86C;MEF2A;RBM42;CYC1 |
translation initiation factor activity | EIF2S3Y;EIF5B;EIF4EB;EIF2B5;MCTS1;EIF3S10;EIF4G3;EIF4A2;EIF4A1A |
EIF4B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF4B here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF4B.
EIF3A; TINF2; npm_alk; PLK1; CSNK2A1; CAMK2D; RPS6KA1; EIF3H; USP11; Ccdc15; KBTBD7; NELL1
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