ELAC1
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Official Full Name
elaC homolog 1 (E. coli)
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Overview
ElaC homolog protein 1 (ELAC1) is a zinc phosphodiesterase, which displays some tRNA 3-processing endonuclease activity. It is probably involved in tRNA maturation, by removing a 3 trailer from precursor tRNA. -
Synonyms
ELAC1; elaC homolog 1 (E. coli); elaC (E. coli) homolog 1; zinc phosphodiesterase ELAC protein 1; D29; tRNA Z (short form); Deleted in Ma29; ELAC 1; ElaC homolog 1; ElaC homolog protein 1; Ribonuclease Z 1; RNase Z 1; tRNA 3 endonuclease 1; tRNA Z; tRNase Z 1; tRNase ZS; OTTHUMP00000163547; tRNA 3 processing endoribonuclease;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- MYC
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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| Human | ELAC1-96H | Recombinant Human ELAC1, His-tagged | E.coli | His |
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| Human | ELAC1-3227H | Recombinant Human ELAC1 Protein, GST-tagged | Wheat Germ | GST |
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| Human | ELAC1-6639HCL | Recombinant Human ELAC1 293 Cell Lysate | HEK293 | N/A |
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| Human | ELAC1-2236H | Recombinant Human ELAC1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK |
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| Human | ELAC1-4329HF | Recombinant Full Length Human ELAC1 Protein, GST-tagged | In Vitro Cell Free System | GST | 363 amino acids |
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| Mouse | ELAC1-5120M | Recombinant Mouse ELAC1 Protein | Mammalian Cell | His |
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| Mouse | ELAC1-2729M-B | Recombinant Mouse ELAC1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | Elac1-520M | Recombinant Mouse Elac1 Protein, MYC/DDK-tagged | HEK293T | MYC/DDK |
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| Mouse | ELAC1-2729M | Recombinant Mouse ELAC1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Zebrafish | ELAC1-944Z | Recombinant Zebrafish ELAC1 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- ELAC1 Related Articles
ELAC1 involved in several pathways and played different roles in them. We selected most pathways ELAC1 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with ELAC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA transport | EIF3C;TRNT1;NCBP1;EIF4BA;EIF1AY;NXT1;PABPC1B;POP1;EIF4EBP3L |
ELAC1 has several biochemical functions, for example, 3-tRNA processing endoribonuclease activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ELAC1 itself. We selected most functions ELAC1 had, and list some proteins which have the same functions with ELAC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 3-tRNA processing endoribonuclease activity | ELAC1;ELAC2 |
| metal ion binding | KLF11;CBS;ZNF548;PLA2G3;ZFP207;ARHGEF1A;PRDM12B;RYBPB;CACNA1D |
ELAC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ELAC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ELAC1.
- Q&As
- Reviews
Q&As (5)
Ask a questionELAC1 protein is involved in maintaining mitochondrial function, and mutations in the ELAC1 gene can contribute to mitochondrial disorders.
Clinical trials investigating the role of ELAC1 protein in mitochondrial disorders are currently underway, aiming to develop targeted therapies.
As of now, there are no specific treatments targeting ELAC1 protein for mitochondrial disorders, but ongoing research may lead to future therapeutic approaches.
In addition to pontocerebellar hypoplasia and mitochondrial disorders, mutations in ELAC1 gene have been linked to infantile hypertrophic cardiomyopathy.
ELAC1 protein plays a role in mitochondrial RNA processing, which is essential for proper cardiac function. Mutations in ELAC1 gene can lead to cardiomyopathy.
Customer Reviews (3)
Write a reviewThe ELAC1 Protein exhibits remarkable stability and functionality, making it an optimal choice for a wide range of applications in various fields.
Its exceptional purity and consistency have consistently yielded reliable and reproducible results, ensuring the accuracy and reliability of my research outcomes.
Their prompt and knowledgeable assistance has been instrumental in overcoming hurdles and has significantly contributed to the success of my research.
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