elp2
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  • Official Full Name
  • elongation protein 2 homolog
  • Background
  • Elongator complex protein 2 is a protein that in humans is encoded by the ELP2 gene.
  • Synonyms
  • ELP2; elongation protein 2 homolog (S. cerevisiae); signal transducer and activator of transcription 3 interacting protein 1 , STATIP1; elongator complex protein 2; FLJ10879; StIP; stIP1; elongator protein 2; STAT3-interacting protein 1; signal transducer
Cat.#:ELP2-1983HTag:GST
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human ELP2, GST-tagged
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Cat.#:ELP2-30857THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ELP2, His-tagged
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Cat.#:ELP2-3992HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human ELP2, MYC/DDK-tagged
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Cat.#:ELP2-5154MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ELP2 Protein
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Cat.#:ELP2-2082RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ELP2 Protein
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Cat.#:ELP2-4026ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ELP2
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Cat.#:ELP2-6616HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human ELP2 293 Cell Lysate
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Involved Pathway

ELP2 involved in several pathways and played different roles in them. We selected most pathways ELP2 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, HATs acetylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with ELP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Chromatin modifying enzymes
CARM1; TADA1; TAF6L; KDM6AL; ENY2; BRPF1; KAT7B; KDM7AB; KDM5B; SMARCE1
Chromatin organization
KDM5A; EPC1; ING3; ACTL6A; KDM6B; SMARCE1; DPY30; SAP18; JADE1; CHD4
HATs acetylate histones
ELP4; CCDC101; C20orf20; MORF4L1; MSL2; KAT7A; MSL1; MORF4L2; MEAF6; DR1

Protein Function

ELP2 has several biochemical functions, for example, contributes_to RNA polymerase II core binding, histone binding, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ELP2 itself. We selected most functions ELP2 had, and list some proteins which have the same functions with ELP2. You can find most of the proteins on our site.
Function
Related Protein
Function contributes_to RNA polymerase II core binding
Related Protein ELP3; IKBKAP; ELP4; ELP2
Function histone binding
Related Protein HIST1H4I; HIST3H3; NCAPD2; HIST1H3G; PHF21A; HIST2H3C; L3MBTL2; PRKCBP1L; USP49; HIST1H4K
Function protein kinase binding
Related Protein KIF13B; GSK3B; PGAM1; TCTN2; DNAJC3; CCNT2B; RAB11FIP2; PRKRIP1; FGF19; HSPB1
Function transcriptional repressor activity, RNA polymerase II transcription factor binding
Related Protein AHRRA; PITX2; ELP2; BHLHE40; CREBBP; MLIP; MINA; AHRRB; RIMKLB; AHRR

Interacting Protein

ELP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ELP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ELP2.
IKBKAP; ETS1; ELP4

ELP2 Related Articles

Srokowski, EM; Woodhouse, KA; et al. Evaluation of the bulk platelet response and fibrinogen interaction to elastin-like polypeptide coatings. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A 102:540-551(2014).
Gu, JX; Sun, DM; et al. Human Elongator complex is involved in cell cycle and suppresses cell growth in 293T human embryonic kidney cells. ACTA BIOCHIMICA ET BIOPHYSICA SINICA 41:831-838(2009).
Liu, WE; Dreher, MR; et al. Tumor accumulation, degradation and pharmacokinetics of elastin-like polypeptides in nude mice. JOURNAL OF CONTROLLED RELEASE 116:170-178(2006).