epb41
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  • Official Full Name
  • erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
  • Background
  • The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
  • Synonyms
  • EPB41; erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked); EL1; protein 4.1; 4.1R; P4.1; EPB4.1; band 4.1; erythrocyte surface protein band 4.1; HE
Cat.#:EPB41-3351HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human EPB41 Protein, GST-tagged
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Cat.#:EPB41-468HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EPB41 Protein, His-tagged
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Cat.#:Epb41-469MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Epb41 Protein, His-tagged
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Cat.#:EPB41-28575THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human EPB41
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Cat.#:EPB41-4036CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken EPB41
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Cat.#:EPB41-560HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human EPB41 cell lysate
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Involved Pathway

EPB41 involved in several pathways and played different roles in them. We selected most pathways EPB41 participated on our site, such as Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with EPB41 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Tight junction
JAM2A; PRKCZ; GNAI2B; LLGL2; CLDN17; VAPA; MYH9; GNAIA; CLDNF; PRKCH

Protein Function

EPB41 has several biochemical functions, for example, 1-phosphatidylinositol binding, actin binding, calmodulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EPB41 itself. We selected most functions EPB41 had, and list some proteins which have the same functions with EPB41. You can find most of the proteins on our site.
Function
Related Protein
Function 1-phosphatidylinositol binding
Related Protein SNX10; ZFYVE16; EPB41; SCIN; SCARB1; PICALM; FRMPD2; WDFY3; SNAP91; MCF2L
Function actin binding
Related Protein SPATA31; HOOK1; SHROOM3; CAPZB; EPB41L3; EPS8L1; SHANK3; PARVAB; CAPZA2; EZR
Function calmodulin binding
Related Protein NETO2; MAP6; MYO5A; CAMK2B; RIT1; MKNK2A; SPHK1; NDUFAF4; CNN3B; AKAP5
Function protein binding
Related Protein SLC25A46; MIS18BP1; KHDC1B; IL17F; TLR4; C1orf35; PRPF40A; TTF2; ASTE1; Ar
Function spectrin binding
Related Protein KIF3A; GNB1; ANK1; ADD2; PDE6G; STX4A; EPB41; USH1C; MYO7A; DYNC1I1
Function structural constituent of cytoskeleton
Related Protein NEFM; TPM1; TUBGCP2; SPTBN2; SPRR2A1; ACTR3; EPB41L3; TUBA8; TUBB5; BKJ

Interacting Protein

EPB41 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPB41 here. Most of them are supplied by our site. Hope this information will be useful for your research of EPB41.
CASK; 4504555; CLIC1; PSMA7; PFAS; SNX3; SNRNP200; NUP155; ATP5L; PNP; HPRT1; GOT2; CSTB; GYPC; TPM2; TXN; COX5B; PCNA