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Recombinant Human EPB41

Cat.No. : EPB41-28575TH
Product Overview : Recombinant full length Human EPB41 with N terminal proprietary tag, 105.27kDa.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Protein length : 720 amino acids
Molecular Weight : 105.270kDa inclusive of tags
Source : Wheat germ
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQ TAAEGDNWCEQKLKASNGDTPTHEDLTKNKERTSESRGLS RLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQE ELREDPDFEIKEGEGLEECSKIEVKEESPQSKAETELKAS QKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPW NFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPC SFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT KELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDL HKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKI SYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQA SALIDRPAPHFERTASKRASRSLDGAAAVDSADRSPRPTS APAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED EPPEQAEPEPTEAWKVEKTHIEVTVPTSNGDQTQKKRERL DGENIYIRHSNLMLEDLDKSQEEIKKHHASISELKKNFME SVPEPRPSEWDKRLSTHSPFRTLNINGQIPTGEGVSTLST
Sequence Similarities : Contains 1 FERM domain.
Gene Name : EPB41 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) [ Homo sapiens ]
Official Symbol : EPB41
Synonyms : EPB41; erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked); EL1; protein 4.1; 4.1R;
Gene ID : 2035
mRNA Refseq : NM_001166005
Protein Refseq : NP_001159477
MIM : 130500
Uniprot ID : P11171
Chromosome Location : 1p33-p32
Pathway : Syndecan-2-mediated signaling events, organism-specific biosystem; Tight junction, organism-specific biosystem; Tight junction, conserved biosystem;
Function : 1-phosphatidylinositol binding; actin binding; protein binding; spectrin binding; structural constituent of cytoskeleton;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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