Recombinant Human EPB41

• Cat.No.: EPB41-28575TH
• Product Overview: Recombinant full length Human EPB41 with N terminal proprietary tag, 105.27kDa.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: Non
• Protein Length: 720 amino acids
• Description: The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Molecular Weight: 105.270kDa inclusive of tags
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQ TAAEGDNWCEQKLKASNGDTPTHEDLTKNKERTSESRGLS RLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGT SLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQE ELREDPDFEIKEGEGLEECSKIEVKEESPQSKAETELKAS QKPIRKHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVC EHLNLLEEDYFGLAIWDNATSKTWLDSAKEIKKQVRGVPW NFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPC SFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQT KELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDL HKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKI SYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVC VEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQA SALIDRPAPHFERTASKRASRSLDGAAAVDSADRSPRPTS APAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKED EPPEQAEPEPTEAWKVEKTHIEVTVPTSNGDQTQKKRERL DGENIYIRHSNLMLEDLDKSQEEIKKHHASISELKKNFME SVPEPRPSEWDKRLSTHSPFRTLNINGQIPTGEGVSTLST
• Sequence Similarities: Contains 1 FERM domain.

Gene Information

• Gene Name: EPB41 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) [ Homo sapiens ]
• Official Symbol: EPB41
• Synonyms: EPB41; erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked); EL1; protein 4.1; 4.1R
• Gene ID: 2035
• mRNA Refseq: NM_001166005
• Protein Refseq: NP_001159477
• MIM: 130500
• Uniprot ID: P11171
• Chromosome Location: 1p33-p32
• Pathway: Syndecan-2-mediated signaling events, organism-specific biosystem; Tight junction, organism-specific biosystem; Tight junction, conserved biosystem
• Function: 1-phosphatidylinositol binding; actin binding; protein binding; spectrin binding; structural constituent of cytoskeleton