• Official Full Name
  • epidermal growth factor receptor pathway substrate 15
  • Background
  • Eps15 (EGFR pathway substrate 15) was originally discovered as a substrate for the kinase activity of EGFR. Eps15 has a tripartite structure comprising an amino terminal portion, which contains three evolutionary conserved EH protein-protein interaction d
  • Synonyms
  • EPS15; epidermal growth factor receptor pathway substrate 15; epidermal growth factor receptor substrate 15; AF 1P; MLLT5; protein AF-1p; ALL1 fused gene from chromosome 1; AF1P; AF-1P
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse EPS15 Protein
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken EPS15
Source (Host):Species:Human
Product nameRecombinant Human EPS15 293 Cell Lysate

Involved Pathway

EPS15 involved in several pathways and played different roles in them. We selected most pathways EPS15 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with EPS15 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein

Protein Function

EPS15 has several biochemical functions, for example, SH3 domain binding, calcium ion binding, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EPS15 itself. We selected most functions EPS15 had, and list some proteins which have the same functions with EPS15. You can find most of the proteins on our site.
Related Protein
Function SH3 domain binding
Related Protein AFAP1L2; ADAM12; CTTNBP2; CASP9; FAM125A; CRB3; ITM2B; REPS1; ELMO1; INPP5J
Function calcium ion binding
Related Protein FSTL1; SYT1B; FBN1; SPARCL1; GSNA; NELL2; FBLN2; S100A6; PRRG2; EPS15L1
Function identical protein binding
Related Protein APP; SOD2; LZTFL1; MNS1; NELL2; APLP1; ATXN10; C1QTNF2; CHMP4B; SOD1
Function polyubiquitin binding
Related Protein PSMD4A; DNAJB2; BAG6; AGL; THRSP; RAD18; RAD23B; FAM175A; EPS15; BRCC3
Function protein binding
Related Protein RWDD1; BLOC1S6; ASIC2; MYOD1; GIMAP5; PSMC1; TAC1; PCM1; WRN; SIPA1L2

Interacting Protein

EPS15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPS15 here. Most of them are supplied by our site. Hope this information will be useful for your research of EPS15.
STON2; Hgs

EPS15 Related Articles

Halder, P; Chen, YC; et al. Identification of Eps15 as Antigen Recognized by the Monoclonal Antibodies aa2 and ab52 of the Wuerzburg Hybridoma Library against Drosophila Brain. PLOS ONE 6:-(2011).
Jakobsson, J; Ackermann, F; et al. Regulation of Synaptic Vesicle Budding and Dynamin Function by an EHD ATPase. JOURNAL OF NEUROSCIENCE 31:13972-13980(2011).