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Official Full Name epidermal growth factor receptor pathway substrate 15
Background Eps15 (EGFR pathway substrate 15) was originally discovered as a substrate for the kinase activity of EGFR. Eps15 has a tripartite structure comprising an amino terminal portion, which contains three evolutionary conserved EH protein-protein interaction d
Synonyms EPS15; epidermal growth factor receptor pathway substrate 15; epidermal growth factor receptor substrate 15; AF 1P; MLLT5; protein AF-1p; ALL1 fused gene from chromosome 1; AF1P; AF-1P
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human EPS15-2722H Recombinant Human EPS15 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Eps15-965M Recombinant Mouse Eps15 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human EPS15-6578HCL Recombinant Human EPS15 293 Cell Lysate HEK293 N/A
    Mouse EPS15-5265M Recombinant Mouse EPS15 Protein Mammalian Cell His
    Chicken EPS15-2939C Recombinant Chicken EPS15 Mammalian Cell His

    EPS15 involved in several pathways and played different roles in them. We selected most pathways EPS15 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with EPS15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Endocytosis FAM21A; RAB11FIP4A; VPS26BL; FAM125A; TGFB3; TSG101; ZFYVE27; MVB12A; BIN1; PDGFRA

    EPS15 has several biochemical functions, for example, SH3 domain binding, calcium ion binding, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EPS15 itself. We selected most functions EPS15 had, and list some proteins which have the same functions with EPS15. You can find most of the proteins on our site.

    Function Related Protein
    SH3 domain binding VASP; ADAM10; PLSCR1; ITM2B; BCAR1; CNTNAP1; HCLS1; ITGB1BP2; NCF1; MVB12A
    calcium ion binding DLL4; ANXA2B; PCDHB11; SCUBE2; CAPN3A; EFEMP2A; GSNB; CAPSLA; THBD; CRB2A
    identical protein binding SDF4; DYNLT1B; UBQLN1; PSME3; AMELX; TLR3; SH2B2; CBY1; DYRK1A; FKBP8
    polyubiquitin binding DNAJB2; EPS15; BRCC3; ZFAND6; BRE; TNIP3; THRSP; PSMD4; AGL; PSMD4B
    protein binding SMAP2; C14orf166; PTPRJ; PTPRS; TMF1; LTF; IL18; ABCF1; cgr2b; TMEM120B

    EPS15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPS15 here. Most of them are supplied by our site. Hope this information will be useful for your research of EPS15.

    STON2; Hgs

    Halder, P; Chen, YC; et al. Identification of Eps15 as Antigen Recognized by the Monoclonal Antibodies aa2 and ab52 of the Wuerzburg Hybridoma Library against Drosophila Brain. PLOS ONE 6:-(2011).
    Jakobsson, J; Ackermann, F; et al. Regulation of Synaptic Vesicle Budding and Dynamin Function by an EHD ATPase. JOURNAL OF NEUROSCIENCE 31:13972-13980(2011).

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