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EXOC5

  • Official Full Name

    exocyst complex component 5

  • Overview

    The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
  • Synonyms

    EXOC5; exocyst complex component 5; SEC10 (S. cerevisiae) like 1 , SEC10 like 1 (S. cerevisiae) , SEC10L1; SEC10; SEC10P; AI448003; Gm76; HSEC10; PRO1912; AI447711; Exocyst complex component Sec10; p71 component of rsec6/8 secretory complex; SEC10L1; SEC10-like 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EXOC5-3560H Recombinant Human EXOC5 Protein, GST-tagged Wheat Germ GST
Human EXOC5-6509HCL Recombinant Human EXOC5 293 Cell Lysate HEK293 N/A
Human EXOC5-4404HF Recombinant Full Length Human EXOC5 Protein, GST-tagged In Vitro Cell Free System GST 708 amino acids
Mouse EXOC5-5374M Recombinant Mouse EXOC5 Protein Mammalian Cell His
Mouse EXOC5-2897M-B Recombinant Mouse EXOC5 Protein Pre-coupled Magnetic Beads HEK293
Mouse EXOC5-2897M Recombinant Mouse EXOC5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat EXOC5-2168R Recombinant Rat EXOC5 Protein Mammalian Cell His
Rat EXOC5-1825R-B Recombinant Rat EXOC5 Protein Pre-coupled Magnetic Beads HEK293
Rat EXOC5-1825R Recombinant Rat EXOC5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque EXOC5-1518R Recombinant Rhesus monkey EXOC5 Protein, His-tagged Mammalian Cell His
Rhesus Macaque EXOC5-1343R-B Recombinant Rhesus Macaque EXOC5 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque EXOC5-1343R Recombinant Rhesus Macaque EXOC5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish EXOC5-6373Z Recombinant Zebrafish EXOC5 Mammalian Cell His
Chicken EXOC5-1960C Recombinant Chicken EXOC5 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EXOC5 Related Articles

EXOC5 involved in several pathways and played different roles in them. We selected most pathways EXOC5 participated on our site, such as Arf6 trafficking events, Assembly of the primary cilium, Cargo trafficking to the periciliary membrane, which may be useful for your reference. Also, other proteins which involved in the same pathway with EXOC5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Arf6 trafficking eventsCTNNA1;CLTC;SCAMP2;EXOC1;SPAG9;CTNND1;PTBP3;EDNRB;CHRM2
Assembly of the primary ciliumLZTFL1;CCT3;KIFAP3B;BBS5;FBF1;MKS1;TTC30A;MARK4;BBS9
Cargo trafficking to the periciliary membraneTCP1;CNGA2;BBS5;MKKS;PKD2;ARF4;CCT5;PROL1;RP2
Insulin PathwayGRB10;EXOC1;EXOC6;GRB14;EXOC3;EXOC5;DOK1
Insulin processingCPE;RAB27A;PCSK2;EXOC5;PCSK1;KIF5A;EXOC8;KIF5B;EXOC3
Membrane TraffickingTFR1B;CNIH3;NAPG;BET1;HIP1R;EXOC6;FTH1B;DAB2;BLOC1S4
Metabolism of proteinsPHC1;SCMH1;TMED10;OTOP2;DNAJC19;DDX11;SPON2;ST3GAL3A;ZDHHC2
Organelle biogenesis and maintenanceMRPL44;MRPS28;MRPL39;GFM1;CNGA5;MRPL53;AURKAIP1;IQCB1;MRPS36

EXOC5 has several biochemical functions, for example, Ral GTPase binding, protein N-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EXOC5 itself. We selected most functions EXOC5 had, and list some proteins which have the same functions with EXOC5. You can find most of the proteins on our site.

Function Related Protein
Ral GTPase bindingMYO1C;LSM2;USP33;EXOC5;RAB34;FLNA;PRKCH;EXOC4;RALBP1
protein N-terminus bindingKCNIP2;SMARCC1;RPA3;SLC6A3;SCFD1;VWF;TSC1;APTX;EXOC4

EXOC5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EXOC5 here. Most of them are supplied by our site. Hope this information will be useful for your research of EXOC5.

TNPO2; PRKCG; CDH2; SOX10; ICA1; ADCK1; ACTR3B; TBX21; pi3p; 15-deoxy-delta(12,14; SNW1; CDC5L

Liu, DM; Novick, P; et al. Bem1p contributes to secretory pathway polarization through a direct interaction with Exo70p. JOURNAL OF CELL BIOLOGY 207:59-72(2014).
Tanaka, T; Iino, M; et al. Sec6 regulated cytoplasmic translocation and degradation of p27 via interactions with Jab1 and Siah1. CELLULAR SIGNALLING 26:2071-2085(2014).
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