Recombinant Human EXOC5 Protein, GST-tagged

• Cat.No.: EXOC5-3560H
• Product Overview: Human EXOC5 full-length ORF ( NP_006535.1, 1 a.a. - 708 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 108.3 kDa
• AA Sequence: MATTAELFEEPFVADEYIERLVWRT PGGGSRGGPEAFDPKRLLEEFVNHI QELQIMDERIQRKVEKLEQQCQKEA KEFAKKVQELQKSNQVAFQHFQELD EHISYVATKVCHLGDQLEGVNTPRQ RAVEAQKLMKYFNEFLDGELKSDVF TNSEKIKEAADIIQKLHLIAQELPF DRFSEVKSKIASKYHDLECQLIQEF TSAQRRGEISRMREVAAVLLHFKGY SHCVDVYIKQCQEGAYLRNDIFEDA GILCQRVNKQVGDIFSNPETVLAKL IQNVFEIKLQSFVKEQLEECRKSDA EQYLKNLYDLYTRTTNLSSKLMEFN LGTDKQTFLSKLIKSIFISYLENYI EVETGYLKSRSAMILQRYYDSKNHQ KRSIGTGGIQDLKERIRQRTNLPLG PSIDTHGETFLSQEVVVNLLQETKQ AFERCHRLSDPSDLPRNAFRIFTIL VEFLCIEHIDYALETGLAGIPSSDS RNANLYFLDVVQQANTIFHLFDKQF NDHLMPLISSSPKLSECLQKKKEII EQMEMKLDTGIDRTLNCMIGQMKHI LAAEQKKTDFKPEDENNVLIQYTNA CVKVCAYVRKQVEKIKNSMDGKNVD TVLMELGVRFHRLIYEHLQQYSYSC MGGMLAICDVAEYRKCAKDFKIPMV LHLFDTLHALCNLLVVAPDNLKQVC SGEQLANLDKNILHSFVQLRADYRS ARLARHFS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EXOC5 exocyst complex component 5 [ Homo sapiens ]
• Official Symbol: EXOC5
• Synonyms: EXOC5; exocyst complex component 5; SEC10 (S. cerevisiae) like 1 , SEC10 like 1 (S. cerevisiae) , SEC10L1; SEC10; SEC10P; SEC10-like 1; exocyst complex component Sec10; HSEC10; PRO1912; SEC10L1; DKFZp666H126
• Gene ID: 10640
• mRNA Refseq: NM_006544
• Protein Refseq: NP_006535
• MIM: 604469
• UniProt ID: O00471