fbxo25
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  • Official Full Name
  • F-box protein 25
  • Background
  • This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
  • Synonyms
  • FBXO25; F-box protein 25; F box only protein 25; F-box only protein 25; FBX25; F-box protein Fbx25; MGC20256; MGC51975
Cat.#:FBXO25-3924HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FBXO25 Protein, GST-tagged
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Cat.#:FBXO25-5738MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse FBXO25 Protein
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Cat.#:FBXO25-2291RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat FBXO25 Protein
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Cat.#:FBXO25-517CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus FBXO25 Protein, His-tagged
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Cat.#:FBXO25-1659RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey FBXO25 Protein, His-tagged
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Cat.#:FBXO25-11744ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish FBXO25
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Cat.#:FBXO25-6303HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human FBXO25 293 Cell Lysate
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Involved Pathway

FBXO25 involved in several pathways and played different roles in them. We selected most pathways FBXO25 participated on our site, such as FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXO25 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
FoxO signaling pathway
STK11; GADD45BA; PLK3; PIK3R1; IGF1RA; KLF2; HOMER1B; SMAD2; PRKAG2; FOXO1

Protein Function

FBXO25 has several biochemical functions, for example, actin binding, protein binding, ubiquitin-protein transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO25 itself. We selected most functions FBXO25 had, and list some proteins which have the same functions with FBXO25. You can find most of the proteins on our site.
Function
Related Protein
Function actin binding
Related Protein FLNC; MYO5A; MYO10; ENC1; WIPF1; GAS2L3; CNN1A; MKL1; INPPL1B; WIPF1A
Function protein binding
Related Protein SLC6A12; DDX11; SERTAD3; IREB2; MLANA; UBASH3B; RPL28; KLRC2; FKBP2; Clec4n
Function ubiquitin-protein transferase activity
Related Protein SIAH2L; RAG1; FBXO2; RNF139; RNF38; UBE2G2; SMURF1; ANAPC4; RNF152; FBXL3

Interacting Protein

FBXO25 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO25 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO25.
CUL1; SKP1; ACTB; b4dyc6_human; HSP90AA1; HSP90AB1; FKBP5; HSP90AB1; PPP5C; ORC4; EP300; CAND1