|Official Full Name||FBJ murine osteosarcoma viral oncogene homolog B|
|Background||The Fos family of nuclear oncogenes includes c-Fos, FosB, Fos-related antigen 1 (FRA1), and Fos-related antigen 2 (FRA2). While most Fos proteins exist as a single isoform, the FosB protein exists as two isoforms: full-length FosB and a shorter form, FosB|
|Synonyms||FOSB; FBJ murine osteosarcoma viral oncogene homolog B; protein fosB; activator protein 1; AP 1; DKFZp686C0818; GOS3; GOSB; G0S3; MGC42291; oncogene FOS B; G0/G1 switch regulatory protein 3; AP-1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
FOSB involved in several pathways and played different roles in them. We selected most pathways FOSB participated on our site, such as Osteoclast differentiation, Cocaine addiction, Amphetamine addiction, which may be useful for your reference. Also, other proteins which involved in the same pathway with FOSB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Osteoclast differentiation||MAPK11; TNFSF11; SPI1; FCGR4; PPP3R2; NFKB1; PPP3CB; LILRA3; FYN; FCGR2C|
|Cocaine addiction||SLC6A3; GRM3; ATF4; GNAI3; GRIN1; CREB3L2; CREB3L3; BDNF; DDC; PDYN|
|Amphetamine addiction||CAMK4; CREB3L2; FOSB; PRKCA; PPP1CA; CREB3L1; CAMK2B; NETO2; ATF2; MAOA|
|Alcoholism||HIST1H4B; GNAS; RAF1; HIST1H3G; H2AFJ; GRIN2B; HIST1H2BP; HRAS; GNB4; CALM1|
FOSB has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FOSB itself. We selected most functions FOSB had, and list some proteins which have the same functions with FOSB. You can find most of the proteins on our site.
|DNA binding||NKX2.4B; NFIL3; KAT6A; TNFAIP3; HIST3H2A; TLR8; VDR; ZNF227; HOXA5; CBFB|
|RNA polymerase II core promoter proximal region sequence-specific DNA binding||TBX3; HAND1; H2AFZ; ESR1; ZSCAN21; NFIA; JUN; FOXJ1; NR3C1; ASCL1|
|transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding||SNAI3; FOSL1; TFAP2A; RBPJL; ATF3; CREB3; DDN; RBPJA; BATF2; SREBF1|
|transcription factor binding||CREG1; HEY1; SRY; HYAL1; NLRP3; SOX8; PIM1; DIP2C; SUMO1; SMARCD3|
|transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding||HLTF; HEYL; TP53; FOXD1; TFE3; CREB3L2; MTF1; FOXJ1; GRHL1; KLF15|
FOSB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FOSB here. Most of them are supplied by our site. Hope this information will be useful for your research of FOSB.