Recombinant Human FBJ Murine Osteosarcoma Viral Oncogene Homolog B
Cat.No. : | FOSB-1230H |
Product Overview : | FOSB encodes a nuclear protein of 338amino acids which has 70% homology with c-Fos, exhibits similar kinetics ofexpression as c-Fos and forms heterodimers with both c-Jun and Jun B whichbind to TRE DNA response elements. Functional homologs of c-Fos and FOSBinclude Fra-1 and Fra-2 genes. |
- Specification
- Gene Information
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Cat. No. : | FOSB-1230H |
Description : | FOSBis a protein that, in humans, is encoded by the FOSB gene. The Fos genefamily consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encodeleucine zipper proteins that can dimerize with proteins of the JUN family,thereby forming the transcription factor complex AP-1. As such, the FOSproteins have been implicated as regulators of cell proliferation,differentiation, and transformation. |
Source : | E. coli |
Species : | Human |
Form : | Recombinant Human FOSB protein(a.a.113-151) at 100 μg/ml in 50 mM Tris-Acetate + pH7.5 + 1 Mm EDTA +20%Glycerol. |
Application : | ELISA; Inhibition Assays; WesternBlotting |
Storage : | Store vial at -20°C to -80°C. Whenstored at the recommended temperature, this protein is stable for 12 months.Please avoid freeze-thaw cycles. |
OfficialSymbol : | FOSB |
Gene Name : | FOSB FBJmurine osteosarcoma viral oncogene homolog B [ Homo sapiens ] |
Synonyms : | FOSB; FBJ murine osteosarcoma viraloncogene homolog B; AP-1; G0S3; GOS3; GOSB; MGC42291;DKFZp686C0818; activator protein 1; oncogene FOS-B; protein fosB; G0/G1switch regulatory protein 3 |
Gene ID : | 2354 |
mRNA Refseq : | NM_001114171 |
Protein Refseq : | NP_001107643 |
MIM : | 164772 |
UniProt ID : | P53539 |
Chromosome Location : | 19q13.3 |
Pathway : | Osteoclast differentiation; TGF-betaReceptor Signaling Pathway |
Function : | protein dimerization activity; sequence-specific DNA binding;transcription factor activity; sequence-specific DNA binding transcriptionfactor activity; DNA binding |
Products Types
◆ Recombinant Protein | ||
FOSB-01H | Recombinant Human FOSB Protein, His-tagged | +Inquiry |
FOSB-4425H | Recombinant Human FOSB Protein, GST-tagged | +Inquiry |
FOSB-12964H | Recombinant Human FOSB, GST-tagged | +Inquiry |
FOSB-28107TH | Recombinant Human FOSB | +Inquiry |
FOSB-1704Z | Recombinant Zebrafish FOSB | +Inquiry |
◆ Lysates | ||
FOSB-6167HCL | Recombinant Human FOSB 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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