Recombinant Human FOSB Protein, GST-tagged

• Cat.No.: FOSB-4425H
• Product Overview: Human FOSB full-length ORF ( AAH40197.1, 1 a.a. - 289 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 57.4 kDa
• AA Sequence: MPGSFVPTVTAITTSQDLQWLVQPT LISSMAQSQGQPLASQPPVVDPYDM PGTSYSTPGMSGYSSGGASGSGGPS TSGTTSGPGPARPARARPRRPREET LTPEEEEKRRVRRERNKLAAAKCRN RRRELTDRLQAETDQLEEEKAELES EIAELQKEKERLEFVLVAHKPGCKI PYEEGPGPGPLAEVRDLPGSAPAKE DGFSWLLPPPPPPPLPFQTSQDAPP NLTASLFTHSEVQVLGDPFPVVNPS YTSSFVLTCPEVSAFAGAQRTSGSD QPSDPLNSPSLLAL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FOSB FBJ murine osteosarcoma viral oncogene homolog B [ Homo sapiens ]
• Official Symbol: FOSB
• Synonyms: FOSB; FBJ murine osteosarcoma viral oncogene homolog B; protein fosB; activator protein 1; AP 1; DKFZp686C0818; GOS3; GOSB; G0S3; MGC42291; oncogene FOS B; G0/G1 switch regulatory protein 3; AP-1
• Gene ID: 2354
• mRNA Refseq: NM_001114171
• Protein Refseq: NP_001107643
• MIM: 164772
• UniProt ID: P53539