FOXL2 Protein, forkhead box L2

FOXL2

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FOXL2

Official Full Name forkhead box L2
Background Forkhead box protein L2 (FOXL2) may function as a transcriptional regulator. FOXL2 is?expressed in the nucleus of somatic cells of the developing gonad and and in the follicular cells of the adult ovary. FOXL2 is also expressed in the developing eyelid.
Synonyms FOXL2; forkhead box L2; BPES; forkhead box protein L2; BPES1; forkhead transcription factor FOXL2; PFRK; POF3; PINTO
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FOXL2-2561H Recombinant Human FOXL2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human FOXL2-4463H Recombinant Human FOXL2 Protein, GST-tagged Wheat Germ GST
    Mouse FOXL2-6000M Recombinant Mouse FOXL2 Protein Mammalian Cell His
    Chicken FOXL2-1981C Recombinant Chicken FOXL2 Mammalian Cell His
    Zebrafish FOXL2-4257Z Recombinant Zebrafish FOXL2 Mammalian Cell His

    FOXL2 involved in several pathways and played different roles in them. We selected most pathways FOXL2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FOXL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    FOXL2 has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, cysteine-type endopeptidase regulator activity involved in apoptotic process. Some of the functions are cooperated with other proteins, some of the functions could acted by FOXL2 itself. We selected most functions FOXL2 had, and list some proteins which have the same functions with FOXL2. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding HMX4; H2AFB1; RUNX1; EMX1; ZNF726; PRIM2; NAT14; MIER2; NR5A1; RPS15
    RNA polymerase II core promoter proximal region sequence-specific DNA binding CEBPG; ZNF486; FIGLA; NKX6-1; ATF3; TLX1; GATA4; BATF; RAX; ASCL2
    cysteine-type endopeptidase regulator activity involved in apoptotic process FOXL2
    estrogen receptor binding NKX3-1; PRMT2; PCNA; ISL1; FOXL2; DDX17; DYX1C1; LEF1; MED1; XBP1
    protein binding CTBP2; ZNHIT1; ASB3; UBAP1; KRAS; RNF115; SF3B2; BFAR; AGPAT1; UBE2V1
    sequence-specific DNA binding SIX4B; TFAP4; TA; HOXA11A; ATF4B2; AHR2; CREB3L1; RAX2; NKX2-6; MEIS3
    transcription factor activity, sequence-specific DNA binding E2F2; ZNF484; DBPA; SLC2A4RG; IKZF4; SPI1; FOXP1A; EOMESB; ZNF471; ETS1
    transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding MZF1; SOX12; GLI2; NFKB2; JUN; POU1F1; IRF1; MEIS1; CREB3L1; PITX2
    ubiquitin conjugating enzyme binding RNF217; DCUN1D5; DCUN1D1; ANKIB1; RNF19B; SIAH2; RNF180; DCUN1D4; TRIM72; ZMYM2

    FOXL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FOXL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FOXL2.

    Esr2; Esr1; sox9_mouse_gene

    Devouassoux-Shisheboran, M; et al. Ovarian cancer: molecular biology. ONCOLOGIE 16:306-312(2014).
    Stewart, CJR; Alexiadis, M; et al. An immunohistochemical and molecular analysis of problematic and unclassified ovarian sex cord stromal tumors. HUMAN PATHOLOGY 44:2774-2781(2013).

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