fgf22
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  • Official Full Name
  • fibroblast growth factor 22
  • Background
  • The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development.
  • Synonyms
  • FGF22; fibroblast growth factor 22; FGF-22
Cat.#:FGF22-563HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Fibroblast Growth Factor 22
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Cat.#:FGF22-28879THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF22
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Cat.#:FGF22-32HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF22 protein, His-tagged
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Cat.#:Fgf22-21MTag:Fc
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse Fibroblast Growth Factor 22, Fc Chimera
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Cat.#:FGF22-5850MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse FGF22 Protein
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Cat.#:Fgf22-940MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Fgf22 protein, His-tagged
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Cat.#:FGF22-1698RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey FGF22 Protein, His-tagged
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Cat.#:FGF22-3724ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish FGF22
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Cat.#:FGF22-6242HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human FGF22 293 Cell Lysate
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Involved Pathway

Fgf22 involved in several pathways and played different roles in them. We selected most pathways Fgf22 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Fgf22 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
CACNA1D; FGF1A; FGF20B; PPM1NA; FGF6A; RPS6KA3; MAP4K4; ACVR1C; RRAS; PPP3CA
Ras signaling pathway
FGF19; GRIN2B; FGFR1; PAK2; CALM2; FGF8; PLA2G3; PRKACG; GNG5; ANGPT1
Rap signaling pathway
ANGPT4; PLCB2; INSR; KRIT1; RAC2; FGF13; GNAQ; RAPGEF1; PLCG1; Pdgfa&Pdgfb
PIK-Akt signaling pathway
LAMA1; YWHAG; MAP2K2; FASLG; COL27A1; PDGFRB; LAMB2; ITGA1; ITGAV; TCL1
Regulation of actin cytoskeleton
FGF6B; PAK3; ITGB7; DIAP3; PDGFRA; MYL2; FGF6; RRAS2; ARHGAP35; VAV2
Pathways in cancer
MMP2; PLCG1; ARHGEF12; BIRC7; BCL2L1; CCNA1; PRKCG; CSF1R; GNB4; FGF10
Melanoma
AKT1; FGF22; PIK3CB; FGF1; MET; CCND1; IGF1; MAPK1; PDGFD; FGF18

Protein Function

Fgf22 has several biochemical functions, for example, fibroblast growth factor receptor binding, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Fgf22 itself. We selected most functions Fgf22 had, and list some proteins which have the same functions with Fgf22. You can find most of the proteins on our site.
Function
Related Protein
Function fibroblast growth factor receptor binding
Related Protein FGF16; FGF8B; FGF18A; FGF10B; FGF9; FGF3; FRS3; KLB; FGF20; FRS2
Function growth factor activity
Related Protein FGF10; PDGFC; GMFB; BMP8B; VHL; Artn; AMBN; IL10; HBEGF; MANF

Fgf22 Related Articles

Yemisci, M; Caban, S; et al. Systemically administered brain-targeted nanoparticles transport peptides across the blood-brain barrier and provide neuroprotection. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 35:469-475(2015).
Rashid, H; Ma, CY; et al. Sp7 and Runx2 molecular complex synergistically regulate expression of target genes. CONNECTIVE TISSUE RESEARCH 55:83-87(2014).