|Official Full Name||growth arrest-specific 2|
|Background||The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Multiple alternatively spliced variants, encoding the same protein, have been identified.|
|Synonyms||GAS2; growth arrest-specific 2; growth arrest-specific protein 2; GAS-2; MGC32610|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
GAS2 involved in several pathways and played different roles in them. We selected most pathways GAS2 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with GAS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Apoptosis||CAPN2; IL3RA; BOKA; HRK; IRF2; CDK5RAP2; PRKAR1B; ADD1; CAPN1; CASP7|
|Apoptotic cleavage of cellular proteins||PLEC; LMNB1; STK24; PLECA; DBNLA; CTNNB1; ADD1; CASP6L2; CLSPN; SATB1|
|Apoptotic execution phase||DFFA; PLECA; PANK1A; DBNLA; GAS2; VIML; LMNB1; SATB1; DSP; HIST1H1A|
|Caspase cascade in apoptosis||TFAP2A; ACTA1; CFL2; DIABLO; DFFA; LMNB1; PARP1; CRADD; CASP2; SATB1|
|Caspase-mediated cleavage of cytoskeletal proteins||GAS2; VIML; DBNLB; SPNA2; ADD1; DBNL; DBNLA; CASP6L2; CASP6L1; PLECA|
|Programmed Cell Death||BAXB; ADD1; DIABLOB; CASP6L1; BCAP31; RNF8; DIABLOA; HMGB2; PANK1A; RIPK3|
GAS2 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by GAS2 itself. We selected most functions GAS2 had, and list some proteins which have the same functions with GAS2. You can find most of the proteins on our site.
GAS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GAS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GAS2.