gbf1
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  • Official Full Name
  • golgi brefeldin A resistant guanine nucleotide exchange factor 1
  • Background
  • Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 is a protein that in humans is encoded by the GBF1 gene.
  • Synonyms
  • GBF1; golgi brefeldin A resistant guanine nucleotide exchange factor 1; Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1; BFA-resistant GEF 1; ARF1GEF; KIAA0248; golgi-specific brefeldin A resistance factor 1; FLJ21500; MGC134877; MGC134878; OTTHUMP00000020365
Cat.#:GBF1-4773HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GBF1 Protein, GST-tagged
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Cat.#:GBF1-654HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human GBF1
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Involved Pathway

GBF1 involved in several pathways and played different roles in them. We selected most pathways GBF1 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GBF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Endocytosis
ZFYVE27; FOLR3; IGF2R; ARAP2; ASAP2B; RAB11FIP2; HSPA6; CXCR4; SH3GL1; PIP5K1AB

Protein Function

GBF1 has several biochemical functions, for example, ARF guanyl-nucleotide exchange factor activity, phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3,5-bisphosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GBF1 itself. We selected most functions GBF1 had, and list some proteins which have the same functions with GBF1. You can find most of the proteins on our site.
Function
Related Protein
Function ARF guanyl-nucleotide exchange factor activity
Related Protein CYTH1; CYTH1A; MON2; ARFGEF2; CYTH1B; CYTH4; CYTH4B; PSD3; CYTH3; FBXO8
Function phosphatidylinositol-3,4,5-trisphosphate binding
Related Protein GBF1; ASAP1; OGT; FERMT2; ARAP1; GAB2; ZFYVE1; ZFYVE16; ARAP2; ARHGAP9
Function phosphatidylinositol-3,5-bisphosphate binding
Related Protein CLVS1; WIPI1; KIF16B; JPH2; WIPI2; WDR45; WDR45L; FAM21C; RAG2; D6WSU116E
Function protein binding
Related Protein E2F5; ACLY; EEF2; JMJD6; NUMB; NACA; BAX; SH2D1B; TRAPPC6A; KLC2

Interacting Protein

GBF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GBF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GBF1.
YWHAG; YWHAB; PTP4A3; TNFRSF1B; COPB1; COPG1; KBTBD7; COPG1; wcaG6; pi3p; IRS4; ZSCAN26; Ccser2; FBXO7; USO1

GBF1 Related Articles

Dorobantu, CM; Ford-Siltz, LA; et al. GBF1-and ACBD3-Independent Recruitment of PI4KIII beta to Replication Sites by Rhinovirus 3A Proteins. JOURNAL OF VIROLOGY 89:1913-1918(2015).
Arst, HN; Hernandez-Gonzalez, M; et al. GBF/Gea mutant with a single substitution sustains fungal growth in the absence of BIG/Sec7. FEBS LETTERS 588:4799-4806(2014).