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GBF1

  • Official Full Name

    golgi brefeldin A resistant guanine nucleotide exchange factor 1

  • Overview

    Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 is a protein that in humans is encoded by the GBF1 gene.
  • Synonyms

    GBF1; golgi brefeldin A resistant guanine nucleotide exchange factor 1; Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1; BFA-resistant GEF 1; ARF1GEF; KIAA0248; golgi-specific brefeldin A resistance factor 1; FLJ21500; MGC134877; MGC134878; OTTHUMP00000020365;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GBF1-654H Recombinant Human GBF1 Mammalian Cell His
Human GBF1-3019H-B Recombinant Human GBF1 Protein Pre-coupled Magnetic Beads HEK293
Human GBF1-3019H Recombinant Human GBF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human GBF1-4773H Recombinant Human GBF1 Protein, GST-tagged Wheat Germ GST
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GBF1 Related Articles

GBF1 involved in several pathways and played different roles in them. We selected most pathways GBF1 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GBF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
EndocytosisMET;ADRB3B;BIN1B;WIPF2;GRK1A;CBL;RAB10;FLT1;STRUMPELLIN

GBF1 has several biochemical functions, for example, ARF guanyl-nucleotide exchange factor activity, phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3,5-bisphosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GBF1 itself. We selected most functions GBF1 had, and list some proteins which have the same functions with GBF1. You can find most of the proteins on our site.

Function Related Protein
ARF guanyl-nucleotide exchange factor activityIQSEC1;CYTH3;CYTH4;CYTH1B;CYTH1A;MON2;FBXO8;GBF1;CYTH2
phosphatidylinositol-3,4,5-trisphosphate bindingMYO1G;ASAP1;PHLDA3;NRGN;PIRT;BTK;PARD3;ZFYVE1;D6WSU116E
phosphatidylinositol-3,5-bisphosphate bindingWDR45L;JPH2;WDR45B;GBF1;SESTD1;SNX3;SH3PXD2B;RAG2;COMMD1
protein bindingTSHZ3;NMUR2;TET3;ADCYAP1R1;CTAGE5;TMBIM6;SYCP1;FSCN1;RTN4

GBF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GBF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GBF1.

YWHAG; YWHAB; PTP4A3; TNFRSF1B; COPB1; COPG1; KBTBD7; COPG1; wcaG6; pi3p; IRS4; ZSCAN26; Ccser2; FBXO7; USO1

Dorobantu, CM; Ford-Siltz, LA; et al. GBF1-and ACBD3-Independent Recruitment of PI4KIII beta to Replication Sites by Rhinovirus 3A Proteins. JOURNAL OF VIROLOGY 89:1913-1918(2015).
Arst, HN; Hernandez-Gonzalez, M; et al. GBF/Gea mutant with a single substitution sustains fungal growth in the absence of BIG/Sec7. FEBS LETTERS 588:4799-4806(2014).
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