This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene is thought to be involved in the differentiation of T helper (Th) cells of the Th1 lineage, and the related mouse gene has been shown to be critical for the development of mature B and T lymphocytes. Read-through transcription exists between this gene and the downstream GIMAP5 (GTPase, IMAP family member 5) gene.
GIMAP1; GTPase, IMAP family member 1; GTPase IMAP family member 1; HIMAP1; IMAP1; IMAP38; immunity associated protein 1
GIMAP1 has several biochemical functions, for example, GTP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GIMAP1 itself. We selected most functions GIMAP1 had, and list some proteins which have the same functions with GIMAP1. You can find most of the proteins on our site.
Function GTP binding
Related Protein EHD1; RRAGD; OPA1; NUDT16; EEF1A1A; RAP1AA; TUBA1C; ARFIP2; ARL4D; GNA12
GIMAP1 Related Articles
Webb, LMC; Bell, SE; et al. Critical role for GIMAP1 in the germinal centre reaction. IMMUNOLOGY 143:66-66(2014).
Webb, LMC; Pascall, JC; et al. Generation and Characterisation of Mice Deficient in the Multi-GTPase Domain Containing Protein, GIMAP8. PLOS ONE 9:-(2014).