This gene encodes a mitochondrial membrane protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. The expression of this gene is induced in BCR/ABL-expressing cells. The encoded protein lacks an N-terminal mitochondrial signal sequence. Experimental studies showed that mitochondrial localization relies on the C-terminal transmembrane domain. In humans, the IAN subfamily genes are located in a cluster at 7q36.1.
GIMAP3; GTPase, IMAP family member 3; GTPase IMAP family member 3; GTPase, IMAP family member 3 pseudogene; Ian4; Gimap5; 2010110D23Rik; GIMAP 3; GTPase of the immune associated protein 3; Immune associated nucleotide 4; Immunity associated nucleotide 4 protein; IAN-4; immunity-associated nucleotide 4 protein
GIMAP3 involved in several pathways and played different roles in them. We selected most pathways GIMAP3 participated on our site, such as XPodNet - protein-protein interactions in the podocyte expanded by STRING, which may be useful for your reference. Also, other proteins which involved in the same pathway with GIMAP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Related Protein
XPodNet - protein-protein interactions in the podocyte expanded by STRING
GIMAP3 has several biochemical functions, for example, GTP binding, nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GIMAP3 itself. We selected most functions GIMAP3 had, and list some proteins which have the same functions with GIMAP3. You can find most of the proteins on our site.
Function GTP binding
Related Protein RAC3B; GBP2; RHOU; RAB40AL; TUBA1A; RASL11B; TUBA4L; RAB1BA; GNA15.1; LRRK1
Function nucleotide binding
Related Protein RPS6KA3B; SMOK2B; CPEB1B; IMPDH2; HNRNPM; C10orf28; CLCN6; NT5C1BA; ROCK2B; SEPT9B