glc8
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  • Official Full Name
  • Background
  • GLC8 is a regulatory subunit of protein phosphatase 1 (Glc7p). This protein involved in glycogen metabolism and chromosome segregation, proposed to regulate Glc7p activity via conformational alteration; ortholog of the mammalian protein phosphatase inhibitor 2. Under normal conditions, Glc8p activates Glc7p, but when Glc8p is over produced, it may also inhibit Glc7p function. Glc8p is activated upon phosphoylation by Pho85p complexed with four cyclins (Pcl6p, Pcl7p, Pcl8p, or Pcl10p).
  • Synonyms
  • Glc8p;Regulatory subunit of protein phosphatase 1 (Glc7p);involved in glycogen metabolism and chromosome segregation;proposed to regulate Glc7p activity via conformational alteration;ortholog of the mammalian protein phosphatase inhibitor 2
Cat.#:GLC8-4377YTag:His
Source (Host):S. cerevisiaeSpecies:S.cerevisiae
Product nameRecombinant Yeast Glc8p, His-tagged
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Cat.#:GLC8-346YTag:His
Source (Host):E. coliSpecies:Yeast
Product nameRecombinant Yeast Glc8p, His-tagged
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Protein Function

GLC8 has several biochemical functions, for example, enzyme activator activity, protein phosphatase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GLC8 itself. We selected most functions GLC8 had, and list some proteins which have the same functions with GLC8. You can find most of the proteins on our site.
Function
Related Protein
Function enzyme activator activity
Related Protein ARL1; GM749; MGST2; CTAGE5; ASAP2; RAB3GAP2; GMFG; ALOX5AP; DNMT3L; PITRM1
Function protein phosphatase inhibitor activity
Related Protein PHACTR1; PPME1; KIAA0649; ENSA; ELFN1; ELFN2; PPP1R14A; PPP1R2P3; PPP1R36; PTN

Interacting Protein

GLC8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GLC8 here. Most of them are supplied by our site. Hope this information will be useful for your research of GLC8.
GLC7; SSB1; PHO85; PPZ2; HSP32; BNI4