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Background GLC8 is a regulatory subunit of protein phosphatase 1 (Glc7p). This protein involved in glycogen metabolism and chromosome segregation, proposed to regulate Glc7p activity via conformational alteration; ortholog of the mammalian protein phosphatase inhibitor 2. Under normal conditions, Glc8p activates Glc7p, but when Glc8p is over produced, it may also inhibit Glc7p function. Glc8p is activated upon phosphoylation by Pho85p complexed with four cyclins (Pcl6p, Pcl7p, Pcl8p, or Pcl10p).
Synonyms Glc8p;Regulatory subunit of protein phosphatase 1 (Glc7p);involved in glycogen metabolism and chromosome segregation;proposed to regulate Glc7p activity via conformational alteration;ortholog of the mammalian protein phosphatase inhibitor 2
    • Species :
    • S.cerevisiae
    • Yeast
    • Source :
    • E.coli
    • Yeast
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Yeast GLC8-346Y Recombinant Yeast Glc8p, His-tagged E.coli His
    S.cerevisiae GLC8-4377Y Recombinant Yeast Glc8p, His-tagged Yeast His

    GLC8 involved in several pathways and played different roles in them. We selected most pathways GLC8 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with GLC8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    GLC8 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by GLC8 itself. We selected most functions GLC8 had, and list some proteins which have the same functions with GLC8. You can find most of the proteins on our site.

    Function Related Protein
    enzyme activator activity APOA5; ALDH1A2; CTAGE5; GM749; GM1679; TAB1; PPP1R12B; DBF4; SEC14L2; LTC4S
    protein phosphatase inhibitor activity PHACTR3; PPP1R10; SH3RF2; PPP1R14D; PPME1; ARPP19; PPP1R14B; PPP1R14A; PTN; SAG

    GLC8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GLC8 here. Most of them are supplied by our site. Hope this information will be useful for your research of GLC8.

    GLC7; SSB1; PHO85; PPZ2; HSP32; BNI4

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