GLRA1

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GLRA1

Official Full Name glycine receptor, alpha 1
Background The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates;postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE),;also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different;isoforms have been found for this gene.
Synonyms GLRA1; glycine receptor, alpha 1; glycine receptor, alpha 1 (startle disease/hyperekplexia) , STHE; glycine receptor subunit alpha-1; startle disease/hyperekplexia; stiff person syndrome; glycine receptor 48 kDa subunit; glycine receptor strychnine-bindin
    • Species :
    • Human
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GLRA1-13307H Recombinant Human GLRA1, GST-tagged E.coli GST
    Human GLRA1-27289TH Recombinant Human GLRA1 Wheat Germ N/A
    Human GLRA1-4970H Recombinant Human GLRA1 Protein, GST-tagged Wheat Germ GST
    Human GLRA1-712HCL Recombinant Human GLRA1 cell lysate N/A
    Rat GLRA1-2567R Recombinant Rat GLRA1 Protein Mammalian Cell His
    Rhesus Macaque GLRA1-1871R Recombinant Rhesus monkey GLRA1 Protein, His-tagged Mammalian Cell His
    Zebrafish GLRA1-8975Z Recombinant Zebrafish GLRA1 Mammalian Cell His

    GLRA1 involved in several pathways and played different roles in them. We selected most pathways GLRA1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with GLRA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Neuroactive ligand-receptor interaction SSTR4; CCKBR; CHRNA1; P2RY11; GABBR1; ADRB3B; GPR50; P2RX3B; BRS3; LTB4R2

    GLRA1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by GLRA1 itself. We selected most functions GLRA1 had, and list some proteins which have the same functions with GLRA1. You can find most of the proteins on our site.

    Function Related Protein
    extracellular-glycine-gated chloride channel activity GLRA2; GLRA1; GLRA4A; GLRBA; SIX2A; GLRB; GLRBB
    contributes_to extracellular-glycine-gated chloride channel activity GLRB; GLRBA; GLRA1; GLRA3; GLRA4B
    glycine binding GLRA4B; SIX2A; GRIN2B; GRIN1; GLRA2; GLRA1; GSS; GNMT; GLRA4A; GRIN3B
    protein binding DNAJA4; XPA; EREG; RBPMS2B; PLXNC1; DAZL; NKD1; Apba1; NAP1L2; SSH1
    taurine binding GLRA1; SLC6A6
    transmitter-gated ion channel activity GLRA3; GLRA4B; GLRA4A; GLRA2; GLRA1; SIX2A

    GLRA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GLRA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GLRA1.

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