|Official Full Name||glycine receptor, alpha 1|
|Background||The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates;postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE),;also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different;isoforms have been found for this gene.|
|Synonyms||GLRA1; glycine receptor, alpha 1; glycine receptor, alpha 1 (startle disease/hyperekplexia) , STHE; glycine receptor subunit alpha-1; startle disease/hyperekplexia; stiff person syndrome; glycine receptor 48 kDa subunit; glycine receptor strychnine-bindin|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
GLRA1 involved in several pathways and played different roles in them. We selected most pathways GLRA1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with GLRA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Neuroactive ligand-receptor interaction||SSTR4; CCKBR; CHRNA1; P2RY11; GABBR1; ADRB3B; GPR50; P2RX3B; BRS3; LTB4R2|
GLRA1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by GLRA1 itself. We selected most functions GLRA1 had, and list some proteins which have the same functions with GLRA1. You can find most of the proteins on our site.
|extracellular-glycine-gated chloride channel activity||GLRA2; GLRA1; GLRA4A; GLRBA; SIX2A; GLRB; GLRBB|
|contributes_to extracellular-glycine-gated chloride channel activity||GLRB; GLRBA; GLRA1; GLRA3; GLRA4B|
|glycine binding||GLRA4B; SIX2A; GRIN2B; GRIN1; GLRA2; GLRA1; GSS; GNMT; GLRA4A; GRIN3B|
|protein binding||DNAJA4; XPA; EREG; RBPMS2B; PLXNC1; DAZL; NKD1; Apba1; NAP1L2; SSH1|
|taurine binding||GLRA1; SLC6A6|
|transmitter-gated ion channel activity||GLRA3; GLRA4B; GLRA4A; GLRA2; GLRA1; SIX2A|
GLRA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GLRA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GLRA1.