glra1
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  • Official Full Name
  • glycine receptor, alpha 1
  • Background
  • The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates;postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE),;also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different;isoforms have been found for this gene.
  • Synonyms
  • GLRA1; glycine receptor, alpha 1; glycine receptor, alpha 1 (startle disease/hyperekplexia) , STHE; glycine receptor subunit alpha-1; startle disease/hyperekplexia; stiff person syndrome; glycine receptor 48 kDa subunit; glycine receptor strychnine-bindin
Cat.#:GLRA1-4970HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GLRA1 Protein, GST-tagged
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Cat.#:GLRA1-13307HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GLRA1, GST-tagged
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Cat.#:GLRA1-27289THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human GLRA1
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Cat.#:GLRA1-2567RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat GLRA1 Protein
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Cat.#:GLRA1-1871RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey GLRA1 Protein, His-tagged
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Cat.#:GLRA1-8975ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GLRA1
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Cat.#:GLRA1-712HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GLRA1 cell lysate
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Involved Pathway

GLRA1 involved in several pathways and played different roles in them. We selected most pathways GLRA1 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GLRA1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Neuroactive ligand-receptor interaction
ADRA1BB; TAAR14L; NMUR1; ADORA2AB; PTGER1; AGTR2; ADORA3; P2RY10; GRM8B; LHB

Protein Function

GLRA1 has several biochemical functions, for example, extracellular-glycine-gated chloride channel activity, contributes_to extracellular-glycine-gated chloride channel activity, glycine binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GLRA1 itself. We selected most functions GLRA1 had, and list some proteins which have the same functions with GLRA1. You can find most of the proteins on our site.
Function
Related Protein
Function extracellular-glycine-gated chloride channel activity
Related Protein SIX2A; GLRB; GLRA1; GLRBB; GLRBA; GLRA2; GLRA4A
Function contributes_to extracellular-glycine-gated chloride channel activity
Related Protein GLRBA; GLRA1; GLRA3; GLRA4B; GLRB
Function glycine binding
Related Protein GLRA1; GLRA4A; GLRA4B; SRR; GRIN2B; GNMT; GRIN3B; GSS; GRIN3A; GLRA2
Function protein binding
Related Protein CSDC2; YIF1A; YTHDC1; GJB6; C6orf108; TOB1A; GRIN2D; PIP5K1A; UNC45B; PSMB1
Function taurine binding
Related Protein SLC6A6; GLRA1
Function transmitter-gated ion channel activity
Related Protein GLRA3; GLRA2; GLRA4B; SIX2A; GLRA4A; GLRA1