glyat
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  • Official Full Name
  • glycine-N-acyltransferase
  • Background
  • The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is;thought to be important in the detoxification of endogenous and xenobiotic acyl-CoAs. Two transcript variants;encoding different isoforms have been found for this gene.
  • Synonyms
  • GLYAT; glycine-N-acyltransferase; glycine N-acyltransferase; ACGNAT; GAT; AAc; HRP-1(CLP); aralkyl-CoA N-acyltransferase; acyl-CoA:glycine N-acyltransferase; aralkyl acyl-CoA N-acyltransferase; aralkyl acyl-CoA:amino acid N-acyltransferase; CAT
Cat.#:GLYAT-3574HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GLYAT, His-tagged
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Cat.#:GLYAT-4995HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GLYAT Protein, GST-tagged
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Cat.#:GLYAT-27658THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GLYAT, His-tagged
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Cat.#:GLYAT-6441MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GLYAT Protein
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Cat.#:GLYAT-1883RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey GLYAT Protein, His-tagged
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Cat.#:GLYAT-5889HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GLYAT 293 Cell Lysate
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Involved Pathway

GLYAT involved in several pathways and played different roles in them. We selected most pathways GLYAT participated on our site, such as Amino Acid conjugation, Amino acid conjugation of benzoic acid, Biological oxidations, which may be useful for your reference. Also, other proteins which involved in the same pathway with GLYAT were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Amino Acid conjugation
GLYATL1; ACSM1; GLYATL2; GLYAT
Amino acid conjugation of benzoic acid
GLYATL2; GLYATL1; GLYAT
Biological oxidations
CYP2C9; SULT1C2; ADH1C; CYP3A5; POMCB; CES1; SLC35B2; GGT6; CYP2C8; CYP11B1
Conjugation of benzoate with glycine
GLYATL1; ACSM1; GLYATL2; GLYAT
Conjugation of carboxylic acids
GLYATL1; GLYATL2; GLYAT; ACSM1
Conjugation of salicylate with glycine
GLYATL1; GLYAT; GLYATL2
Metabolism
SAT1B; UGT1B1; SLC25A32A; KCNS3A; UCP2; ACOT9.1; DPEP2; KCNB1; ACOT11B; CPTP
Phase II conjugation
UGT1B4; GLYATL1; Sult2a6; GLYAT; SLC35D1A; SLC35B3; UGT1B2; SLC35B2; UGT1B7; UGT1B5

Protein Function

GLYAT has several biochemical functions, for example, glycine N-acyltransferase activity, glycine N-benzoyltransferase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GLYAT itself. We selected most functions GLYAT had, and list some proteins which have the same functions with GLYAT. You can find most of the proteins on our site.
Function
Related Protein
Function glycine N-acyltransferase activity
Related Protein GLYAT; GLYATL1; GLYATL2; KEG1; GM4952
Function glycine N-benzoyltransferase activity
Related Protein GLYAT
Function protein binding
Related Protein NUSAP1; SEC63; CEP44; RYR1B; NPM3; INS; TRIM74; DDOST; CCDC12; VAMP3
Function transferase activity, transferring acyl groups
Related Protein ZDHHC16; ESCO1; AANAT1; CML2; LIPT2; TGM2B; GM4952; ZDHHC24; ZDHHC16B; GGACT.1

Interacting Protein

GLYAT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GLYAT here. Most of them are supplied by our site. Hope this information will be useful for your research of GLYAT.
KRTAP10-8; NOTCH2NL; PA; PTN; RBM48; VOPP1

GLYAT Related Articles

Dempsey, DR; Bond, JD; et al. Expression, purification, and characterization of mouse glycine N-acyltransferase in Escherichia coli. PROTEIN EXPRESSION AND PURIFICATION 97:23-28(2014).
Badenhorst, CPS; van der Sluis, R; et al. Glycine conjugation: importance in metabolism, the role of glycine N-acyltransferase, and factors that influence interindividual variation. EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY 9:1139-1153(2013).