GLYAT

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GLYAT

Official Full Name glycine-N-acyltransferase
Background The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is;thought to be important in the detoxification of endogenous and xenobiotic acyl-CoAs. Two transcript variants;encoding different isoforms have been found for this gene.
Synonyms GLYAT; glycine-N-acyltransferase; glycine N-acyltransferase; ACGNAT; GAT; AAc; HRP-1(CLP); aralkyl-CoA N-acyltransferase; acyl-CoA:glycine N-acyltransferase; aralkyl acyl-CoA N-acyltransferase; aralkyl acyl-CoA:amino acid N-acyltransferase; CAT
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GLYAT-27658TH Recombinant Human GLYAT, His-tagged E.coli His
    Human GLYAT-3574H Recombinant Human GLYAT, His-tagged E.coli His
    Human GLYAT-4995H Recombinant Human GLYAT Protein, GST-tagged Wheat Germ GST
    Human GLYAT-5889HCL Recombinant Human GLYAT 293 Cell Lysate HEK293 N/A
    Mouse GLYAT-6441M Recombinant Mouse GLYAT Protein Mammalian Cell His
    Rhesus Macaque GLYAT-1883R Recombinant Rhesus monkey GLYAT Protein, His-tagged Mammalian Cell His

    GLYAT involved in several pathways and played different roles in them. We selected most pathways GLYAT participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with GLYAT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Amino Acid conjugation GLYATL1; ACSM1; GLYAT; GLYATL2
    Amino acid conjugation of benzoic acid GLYATL1; GLYAT; GLYATL2
    Biological oxidations ADH1C; SLC26A2; GGT6; SULT2ST2; CYP2C9; GLYATL1; CYP4F12; CYP2F1; CYP2A13; Sult2a2
    Conjugation of benzoate with glycine GLYATL2; GLYAT; GLYATL1; ACSM1
    Conjugation of carboxylic acids GLYATL1; GLYAT; ACSM1; GLYATL2
    Conjugation of salicylate with glycine GLYATL1; GLYAT; GLYATL2
    Metabolism GCKR; GCHFR; GPHN; UCP3; ARL2; Agmo; CSPG5B; MED22; ADHFE1; ATP5L
    Phase II conjugation SLC26A2; GLYATL1; BPNT1; GLYATL2; GGTLC1; ABHD14B; ABHD10; SULT4A1; SULT1ST6; SLC35B2

    GLYAT has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by GLYAT itself. We selected most functions GLYAT had, and list some proteins which have the same functions with GLYAT. You can find most of the proteins on our site.

    Function Related Protein
    glycine N-acyltransferase activity GLYATL1; GLYAT; GLYATL2; GM4952; KEG1
    glycine N-benzoyltransferase activity GLYAT
    protein binding DEPDC6; H2AFY; IFT20; PUM2; FAM129A; FBXO6; SERPINB3C; CDK18; BBOX1; FFAR2
    transferase activity, transferring acyl groups KEG1; CHATB; NAT14; CDYL; MBOAT2; DGAT2L6; HHATLA; NMT1B; NAT15; ACAA1A

    GLYAT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GLYAT here. Most of them are supplied by our site. Hope this information will be useful for your research of GLYAT.

    KRTAP10-8; NOTCH2NL; PA; PTN; RBM48; VOPP1

    Dempsey, DR; Bond, JD; et al. Expression, purification, and characterization of mouse glycine N-acyltransferase in Escherichia coli. PROTEIN EXPRESSION AND PURIFICATION 97:23-28(2014).
    Badenhorst, CPS; van der Sluis, R; et al. Glycine conjugation: importance in metabolism, the role of glycine N-acyltransferase, and factors that influence interindividual variation. EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY 9:1139-1153(2013).

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