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GNB3

  • Official Full Name

    guanine nucleotide binding protein (G protein), beta polypeptide 3

  • Overview

    G-Protein b3 (GNB3) is a guanine nucleotide-binding protein (G protein). G-proteins are involved as a modulator or transducer in various transmembrane signaling systems.
  • Synonyms

    GNB3; guanine nucleotide binding protein (G protein), beta polypeptide 3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; transducin beta chain 3; G protein, beta-3 subunit; hypertension associated protein; GTP-binding regulatory protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GNB3-299H Recombinant Human guanine nucleotide binding protein (G protein), beta polypeptide 3, His-tagged E.coli His
Human GNB3-5861HCL Recombinant Human GNB3 293 Cell Lysate HEK293 N/A
Human GNB3-5370HF Recombinant Full Length Human GNB3 Protein, GST-tagged In Vitro Cell Free System GST 340 amino acids
Human GNB3-5056H Recombinant Human GNB3 Protein, GST-tagged Wheat Germ GST
Rat GNB3-2602R Recombinant Rat GNB3 Protein Mammalian Cell His
Rat GNB3-2257R Recombinant Rat GNB3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GNB3-2257R-B Recombinant Rat GNB3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque GNB3-1898R Recombinant Rhesus monkey GNB3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque GNB3-1718R Recombinant Rhesus Macaque GNB3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque GNB3-1718R-B Recombinant Rhesus Macaque GNB3 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

GNB3 involved in several pathways and played different roles in them. We selected most pathways GNB3 participated on our site, such as Ras signaling pathway, Chemokine signaling pathway, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNB3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ras signaling pathwayMAPK1;FLT4;FGF14;RASAL3;PIK3CA;ABL1;PLA2G2F;PLA2G3;AKT1
Chemokine signaling pathwayVAV2;CRK;CCL24;CXCL5;CXCR3;CXCR2;RAF1;CXCL14;PRKCZ
PIK-Akt signaling pathwayFGF8;PRKAA2;ITGB3;IFNAR1;BAD;PIK3CG;VEGFA;TEK;COL24A1
Circadian entrainmentGNAI2;GRIA2;GNG13;PRKACB;CALM3;GRIA1;GNG11;ADCYAP1R1;GRIN2C
Retrograde endocannabinoid signalingGABRR3;GRM5;GABRE;PLCB2;PTGS2;GABRA5;FAAH;GNG12;GABRA1
Glutamatergic synapseGRM6;SLC1A7;GRIK4;GNB1;GNG4;GNG13;PLCB3;GRIK1;GRIN3A
Cholinergic synapsePIK3CA;BCL2;PRKCB;KCNQ3;PRKACB;GNB2;GNGT2;GNGT1;GNG2
Serotonergic synapseGNG11;CYP2D26;PRKACA;CYP2C39;CYP4X1;KCND2;HTR6;NRAS;GNG10
GABAergic synapsePLCL1;HAP1;GNG4;GNAI3;GPHN;GNG8;GABRP;GABRA3;GABRR2
Dopaminergic synapseCALM4;PPP2R2A;GNAI1;SLC6A3;GRIA4;PRKCA;PPP2R3A;GNG11;PPP2R5D
Taste transductionTAS2R117;TAS2R7;TAS2R123;GNB3;TAS2R104;TAS2R120;TAS2R140;ITPR3;KCNB1
AlcoholismHIST1H4K;H2AFX;GNG4;HIST1H3H;HIST1H2AG;HIST2H3C;HIST1H2BG;ADORA2A;SHC2
Pathways in cancerPDGFRA;FIGF;WNT6;FGF12;CBL;TGFB1;PIK3CD;CCNA1;NFKB1

GNB3 has several biochemical functions, for example, GTPase activity, GTPase binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GNB3 itself. We selected most functions GNB3 had, and list some proteins which have the same functions with GNB3. You can find most of the proteins on our site.

Function Related Protein
GTPase activityGNAV1;IFT22;RAB1;TUBB6;SRPR;GNG11;RAB18;DDX3X;TUFM
GTPase bindingBNIP3;SH3GL1;GNB1;EPRS;GNB2;AIMP1;GM5506;MARCH5;STOML2
protein bindingGPBP1;STIM1;PLCG2;MSR1;UBE2F;KIAA0247;UBA3;NCAM1A;HAT1
signal transducer activityGPR34L;SECTM1;CC2D1A;NPFFR1L1;CHRM5A;GHSRA;GRM6A;IL1R1;GNRHR3

GNB3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNB3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNB3.

CXCR5; NS; ERBB2; P; ESR2; CDC5L

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