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GNG4

Official Full Name

guanine nucleotide binding protein (G protein), gamma 4
Overview

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 is a protein that in humans is encoded by the GNG4 gene.
Synonyms

GNG4; guanine nucleotide binding protein (G protein), gamma 4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4; GNGT4; Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-4 subunit; OTTHUMP00000038436; OTTHUMP00000038437; guanine nucleotide binding protein 4;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
DDK
MYC
Myc|DDK

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GNG4-422H	Recombinant Human guanine nucleotide binding protein (G protein), gamma 4, His-tagged	E.coli	His		Inquiry
Human	GNG4-5023H	Recombinant Human GNG4, His-tagged	E.coli	His		Inquiry
Human	GNG4-13364H	Recombinant Human GNG4, GST-tagged	E.coli	GST	1-75a.a.	$319 / 25ug
Human	GNG4-5389HF	Recombinant Full Length Human GNG4 Protein, GST-tagged	In Vitro Cell Free System	GST	75 amino acids	Inquiry
Human	GNG4-5070H	Recombinant Human GNG4 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GNG4-1950H	Recombinant Human GNG4 Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	GNG4-939H	Recombinant Human GNG4 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	GNG4-7038M	Recombinant Mouse GNG4 Protein	Mammalian Cell	His		Inquiry
Mouse	GNG4-3775M-B	Recombinant Mouse GNG4 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	Gng4-1036M	Recombinant Mouse Gng4 Protein, MYC/DDK-tagged	HEK293T	MYC/DDK		Inquiry
Mouse	GNG4-3775M	Recombinant Mouse GNG4 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein
GNG4 Related Articles

GNG4 involved in several pathways and played different roles in them. We selected most pathways GNG4 participated on our site, such as Ras signaling pathway, Chemokine signaling pathway, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNG4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Ras signaling pathway	SHOC2;PIK3R3;PDGFD;PLD1;RHOA;FGF21;GNGT2;FGF11;SHC4
Chemokine signaling pathway	NFKB1;PIK3R2;PREX1;PRKACG;GNG11;PIK3CB;GRK6;CCL4L2;NFKBIB
PIK-Akt signaling pathway	LPAR2;PRKAA2;CD19;VEGFC;PPP2R1B;ITGB8;GNB4;THBS3;HRAS
Circadian entrainment	CALM3;KCNJ6;PLCB1;CALML5;FOS;GNG12;PRKG1;GNGT2;CALM4
Retrograde endocannabinoid signaling	GABRG2;ITPR1;GABRB3;GABRA4;PRKACA;MAPK12;SLC17A8;GNAI2;GNB4
Glutamatergic synapse	PLCB1;GNAQ;PPP3R2;PRKACG;PLA2G4A;SHANK1;GNAI1;GRM7;ADRBK2
Cholinergic synapse	MAPK1;GNG2;NRAS;KCNQ5;KCNQ2;GNG8;GNB3;PIK3R5;GNG3
Serotonergic synapse	GNG13;HTR2C;GNG10;GNG2;GNAO1;TPH1;HTR3B;PLA2G4A;GNG7
GABAergic synapse	GNAI1;GNG13;GNG12;GABARAP;PRKACB;GABRA5;GLUL;GNG2;GABBR1
Dopaminergic synapse	PRKCG;GRIA1;GSK3A;PPP2R5E;CREB3L1;DRD3;ARNTL;CREB3L2;KCNJ9
Alcoholism	CAMKK1;CALML3;GNG7;GNG4;MAPK3;HIST1H2AP;HIST2H2AA2;HIST1H2AL;HIST1H2BO
Pathways in cancer	CCND1;PRKCG;FGF10;ABL1;SMAD2;GNA12;KIT;FZD9;BMP2

GNG4 has several biochemical functions, for example, protein binding, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GNG4 itself. We selected most functions GNG4 had, and list some proteins which have the same functions with GNG4. You can find most of the proteins on our site.

Function	Related Protein
protein binding	FGF7;VPS33B;NR1I2;DCAF7;FYB;CCDC70;CCR3;RAB4B;TPPP
signal transducer activity	STAT5A;OLFR8;GPR184;CTNNB1;BAI2;GNA12A;TAAR10A;MRGPRA5;SECTM1

GNG4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNG4 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNG4.

Kcnk2

Padigel, UM; Stein, L; et al. Signaling through G alpha i2 protein is required for recruitment of neutrophils for antibody-mediated elimination of larval Strongyloides stercoralis in mice. JOURNAL OF LEUKOCYTE BIOLOGY 81:1120-1126(2007).

Fabbri, E; Selva, C; et al. Identification and properties of a Gs protein in catfish liver membranes. GENERAL AND COMPARATIVE ENDOCRINOLOGY 125:340-348(2002).