gng4
Share
  • Official Full Name
  • guanine nucleotide binding protein (G protein), gamma 4
  • Background
  • Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 is a protein that in humans is encoded by the GNG4 gene.
  • Synonyms
  • GNG4; guanine nucleotide binding protein (G protein), gamma 4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4; GNGT4; Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-4 subunit; OTTHUMP00000038436; OTTHUMP00000038437; guanine nucleotide binding protein 4
Cat.#:GNG4-1950HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human GNG4 Protein, MYC/DDK-tagged
+Inquiry
Cat.#:GNG4-5070HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GNG4 Protein, GST-tagged
+Inquiry
Cat.#:GNG4-13364HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GNG4, GST-tagged
+Inquiry
Cat.#:GNG4-422HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human guanine nucleotide binding protein (G protein), gamma 4, His-tagged
+Inquiry
Cat.#:GNG4-5023HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GNG4, His-tagged
+Inquiry
Cat.#:GNG4-7038MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GNG4 Protein
+Inquiry

Involved Pathway

GNG4 involved in several pathways and played different roles in them. We selected most pathways GNG4 participated on our site, such as Ras signaling pathway, Chemokine signaling pathway, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNG4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ras signaling pathway
GNG7; BRAP; ETS2; RAB5C; GRIN2A; VEGFC; KRAS; CALML5; HTR7; PLCG2
Chemokine signaling pathway
CXCR3; XCL2; PRKACB; IKBKB; PIK3CA; AKT1; GNG7; RLN1; STAT5B; CRKL
PIK-Akt signaling pathway
SOS1; VTN; SYK; PIK3R1; YWHAH; IFNA17; IRS1; GNGT2; PRL; FGF18
Circadian entrainment
GRIN2B; GNAS; GNG13; GRIA3; GNG7; PRKCB; GNAO1; PLCB1; GNGT2; GNG8
Retrograde endocannabinoid signaling
PLCB4; PLCB3; MAPK13; PLCB2; GNB3; PRKACA; PRKCG; MAPK9; MAPK12; GABRA1
Glutamatergic synapse
GNG7; GRIK1; PRKCA; PLA2G4F; PPP3R1; GNAO1; PRKACG; GRM4; SLC17A7; GNB1
Cholinergic synapse
CREB3; CAMK2B; GNG10; CHRNB2; CAMK2A; ITPR3; FOS; CHAT; GNG13; KCNJ2
Serotonergic synapse
GNG13; SLC18A1; PLA2G4A; ALOX5; APP; SLC6A4; GNAO1; CYP2C38; CYP2D26; HTR3A
GABAergic synapse
GABBR2; GABRB2; GABRB1; GABRQ; GPHN; GNG8; GABRR3; GNG12; GNAI1; GABRA6
Dopaminergic synapse
PLCB1; PPP2R2D; ITPR3; GNAI2; DRD4; GRIA3; GRIA1; SLC18A2; CALM1; KIF5B
Morphine addiction
ADRBK2; PDE7A; PDE4D; GNG7; PDE4C; GNG4; PRKCG; GABBR1; GABRG1; PRKCA
Alcoholism
HIST1H4F; BRAF; GM14482; ATF2; CALML3; GNGT1; HIST2H3C2; GNG3; HIST1H2BL; HIST2H2BE
Pathways in cancer
PTK2; TGFBR1; HDAC2; IL-8; LAMC2; BCR; TRAF4; KITLG; FGF19; ZBTB16

Protein Function

GNG4 has several biochemical functions, for example, protein binding, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GNG4 itself. We selected most functions GNG4 had, and list some proteins which have the same functions with GNG4. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein ZNF3; ZFP423; CERK; SLC25A46; SDHA; WAC; GM885; LGR6; TFF1; CDC42EP2
Function signal transducer activity
Related Protein BCAR1; VMN2R26; SH2B1; TFG; TAAR10C; CXCR7B; HTR2CL1; VMN1R40; OLFCS2; GULP1

Interacting Protein

GNG4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNG4 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNG4.
Kcnk2

GNG4 Related Articles

Padigel, UM; Stein, L; et al. Signaling through G alpha i2 protein is required for recruitment of neutrophils for antibody-mediated elimination of larval Strongyloides stercoralis in mice. JOURNAL OF LEUKOCYTE BIOLOGY 81:1120-1126(2007).
Fabbri, E; Selva, C; et al. Identification and properties of a Gs protein in catfish liver membranes. GENERAL AND COMPARATIVE ENDOCRINOLOGY 125:340-348(2002).