gng4
Share
  • Official Full Name
  • guanine nucleotide binding protein (G protein), gamma 4
  • Background
  • Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 is a protein that in humans is encoded by the GNG4 gene.
  • Synonyms
  • GNG4; guanine nucleotide binding protein (G protein), gamma 4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4; GNGT4; Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-4 subunit; OTTHUMP00000038436; OTTHUMP00000038437; guanine nucleotide binding protein 4
Cat.#:GNG4-1950HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human GNG4 Protein, MYC/DDK-tagged
+Inquiry
Cat.#:GNG4-5070HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GNG4 Protein, GST-tagged
+Inquiry
Cat.#:GNG4-13364HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GNG4, GST-tagged
+Inquiry
Cat.#:GNG4-422HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human guanine nucleotide binding protein (G protein), gamma 4, His-tagged
+Inquiry
Cat.#:GNG4-5023HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GNG4, His-tagged
+Inquiry
Cat.#:GNG4-7038MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GNG4 Protein
+Inquiry

Involved Pathway

GNG4 involved in several pathways and played different roles in them. We selected most pathways GNG4 participated on our site, such as Ras signaling pathway, Chemokine signaling pathway, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNG4 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ras signaling pathway
TBK1; GNG3; CALM3; PIK3CB; PLA2G4F; EFNA4; PRKCA; PRKACG; GNB4; IGF1
Chemokine signaling pathway
CXCL10; ARRB2; NCF1; SHC2; GNAI1; CCL8; GNG3; ADRBK2; CCL24; PLCB2
PIK-Akt signaling pathway
FGF2; INSR; IFNA8; TEK; LAMA4; NFKB1; IBSP; COL27A1; PDGFA; GYS2
Circadian entrainment
KCNJ6; GNG3; MAPK3; PRKCB; CACNA1G; PRKACB; MAPK1; ADCYAP1R1; PER1; GRIN2A
Retrograde endocannabinoid signaling
GABRA1; MAPK12; GABRA3; GRM5; GNG12; GNG2; GABRP; GABRR2; GABRG2; GABRD
Glutamatergic synapse
PPP3CC; GNG13; GRIN2D; GRIK1; MAPK1; GRM8; GNAS; PPP3R2; GRM6; SLC38A2
Cholinergic synapse
CAMK2G; PLCB2; KCNQ2; MAPK3; KCNJ14; CAMK2D; Adcy4; GNA11; GNG11; PRKACG
Serotonergic synapse
HTR3E; NRAS; GNG8; MAOA; HTR4; HTR1B; GNB4; PLA2G4D; HTR2C; MAPK1
GABAergic synapse
HAP1; GABRA1; GAD2; GNGT1; GLS2; GNG10; GNB3; GABRQ; GNG13; SLC6A1
Dopaminergic synapse
KIF5B; MAPK12; SCN1A; GNG4; PPP2R2B; CALM1; PLCB3; CAMK2A; ATF4; PPP2R5B
Morphine addiction
PDE4C; GABRG1; PRKACA; GRK4; GRK5; GABRR1; ARRB2; GNAO1; LOC100328615; GABRA6
Alcoholism
HIST1H2AH; HIST1H4H; MAPK1; NTRK2; CALM1; DRD1A; HDAC2; HDAC1; HIST1H4K; HIST1H3A
Pathways in cancer
CCDC6; PTGER1; CSF1R; NFKB2; FGF12; RASGRP3; FZD5; WNT8A; RARA; WNT6

Protein Function

GNG4 has several biochemical functions, for example, protein binding, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GNG4 itself. We selected most functions GNG4 had, and list some proteins which have the same functions with GNG4. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein SHMT2; FAM125B; TCEB3B; ANXA7; LRR1; TFIP11; VAV3; NID2; SALL1; SFPQ
Function signal transducer activity
Related Protein DRD1A; FPR3; VMN1R41; RRH; MRGPRH; MAS1; FPR-RS3; DRD4B; CTNNB1; PARAPINOPSINB

Interacting Protein

GNG4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNG4 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNG4.
Kcnk2

GNG4 Related Articles

Padigel, UM; Stein, L; et al. Signaling through G alpha i2 protein is required for recruitment of neutrophils for antibody-mediated elimination of larval Strongyloides stercoralis in mice. JOURNAL OF LEUKOCYTE BIOLOGY 81:1120-1126(2007).
Fabbri, E; Selva, C; et al. Identification and properties of a Gs protein in catfish liver membranes. GENERAL AND COMPARATIVE ENDOCRINOLOGY 125:340-348(2002).