gng4
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  • Official Full Name
  • guanine nucleotide binding protein (G protein), gamma 4
  • Background
  • Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 is a protein that in humans is encoded by the GNG4 gene.
  • Synonyms
  • GNG4; guanine nucleotide binding protein (G protein), gamma 4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4; GNGT4; Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-4 subunit; OTTHUMP00000038436; OTTHUMP00000038437; guanine nucleotide binding protein 4
Cat.#:GNG4-1950HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human GNG4 Protein, MYC/DDK-tagged
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Cat.#:GNG4-5070HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GNG4 Protein, GST-tagged
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Cat.#:GNG4-13364HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GNG4, GST-tagged
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Cat.#:GNG4-422HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human guanine nucleotide binding protein (G protein), gamma 4, His-tagged
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Cat.#:GNG4-5023HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GNG4, His-tagged
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Cat.#:GNG4-7038MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GNG4 Protein
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Involved Pathway

GNG4 involved in several pathways and played different roles in them. We selected most pathways GNG4 participated on our site, such as Ras signaling pathway, Chemokine signaling pathway, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNG4 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ras signaling pathway
FASLG; PAK7; SHC1; PLA2G2D; MLLT4; FGFR4; RELA; RASSF5; PAK3; MAPK9
Chemokine signaling pathway
ITK; PIK3CG; GNG12; XCL2; Adcy4; AKT1; DOCK2; SHC2; PLCB3; GNAI1
PIK-Akt signaling pathway
Kitl; PPP2R2C; Il2; MAPK3; IGF1R; BAD; FGF6; PPP2R5C; YWHAZ; GNG4
Circadian entrainment
GNAI1; MAPK1; GRIN2B; GNG10; GRIN2C; GRIN1; GRIA1; PLCB2; AKR1C1; CAMK2G
Retrograde endocannabinoid signaling
GNAI3; PRKCG; GABRA2; MAPK1; GNAO1; GABRE; GABRA6; PLCB2; Adcy4; GABRA5
Glutamatergic synapse
GNAI1; GRM4; GNG13; SLC17A6; GNG11; GRIN2C; GNAQ; PRKCB; PLD2; GNB3
Cholinergic synapse
GNG3; GNG2; GNAI2; GNB2; CHAT; HRAS; GNAI1; PIK3CA; GNAO1; GNG10
Serotonergic synapse
TPH2; ALOX12; GNAI3; NRAS; GNG3; GNG4; ALOX5; CYP2C37; PRKACA; APP
GABAergic synapse
GNGT1; GABRA1; GNG12; PRKACB; GABRR3; SLC6A1; GABRR1; GNGT2; GABRA5; PLCL1
Dopaminergic synapse
PPP2R5E; PPP2R3A; GSK3A; PPP2CB; ATF6B; ATF4; CALML3; MAPK12; GRIA3; GNB1
Morphine addiction
GABRR3; GABRA6; LOC100328615; GRK6; PDE4D; ARRB1; Adcy4; GABRG1; GNB1; PDE2A
Alcoholism
GNG10; H2AFY; GNG12; HIST1H2AH; GNGT1; HIST1H2BE; DDC; CREB3; HIST3H2BB-PS; HIST1H2AF
Pathways in cancer
BCR; MAP2K2; ITGA6; AXIN1; PTEN; MAP2K1; TCF7L2; EPAS1; PLCB2; FZD7

Protein Function

GNG4 has several biochemical functions, for example, protein binding, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GNG4 itself. We selected most functions GNG4 had, and list some proteins which have the same functions with GNG4. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein DLX4; MTA1; PAFAH1B1; ADAM23; DDX39A; CARHSP1; KCNIP2; PRCC; GAS2L3; MIF4GD
Function signal transducer activity
Related Protein ECT2; EMR4; OPN1MW3; PTGER1B; AVP; OLFR49; GPR173; GPR31B; OLFCD2; SH2B1

Interacting Protein

GNG4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNG4 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNG4.
Kcnk2

GNG4 Related Articles

Padigel, UM; Stein, L; et al. Signaling through G alpha i2 protein is required for recruitment of neutrophils for antibody-mediated elimination of larval Strongyloides stercoralis in mice. JOURNAL OF LEUKOCYTE BIOLOGY 81:1120-1126(2007).
Fabbri, E; Selva, C; et al. Identification and properties of a Gs protein in catfish liver membranes. GENERAL AND COMPARATIVE ENDOCRINOLOGY 125:340-348(2002).