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Official Full Name guanine nucleotide binding protein (G protein), gamma 4
Background Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 is a protein that in humans is encoded by the GNG4 gene.
Synonyms GNG4; guanine nucleotide binding protein (G protein), gamma 4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4; GNGT4; Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-4 subunit; OTTHUMP00000038436; OTTHUMP00000038437; guanine nucleotide binding protein 4
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GNG4-13364H Recombinant Human GNG4, GST-tagged E.coli GST
    Human GNG4-1950H Recombinant Human GNG4 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human GNG4-422H Recombinant Human guanine nucleotide binding protein (G protein), gamma 4, His-tagged E.coli His
    Human GNG4-5023H Recombinant Human GNG4, His-tagged E.coli His
    Human GNG4-5070H Recombinant Human GNG4 Protein, GST-tagged Wheat Germ GST
    Mouse GNG4-7038M Recombinant Mouse GNG4 Protein Mammalian Cell His

    GNG4 involved in several pathways and played different roles in them. We selected most pathways GNG4 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNG4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ras signaling pathway PDGFD; NGF; ABL2; RRAS2; PLA2G4A; KRAS; RAPGEF5; HRAS; PLA2G2E; EFNA4
    Chemokine signaling pathway GNAI3; GM1987; KRAS; NFKB1; GNG2; CXCR6; SHC4; CCL19; SHC1; PRKACG
    PIK-Akt signaling pathway IFNA5; BRCA1; Il4ra; GH1; ITGA2B; ITGA2; LPAR5; IL2RG; PTEN; CREB3L3
    Circadian entrainment NOS1; CAMK2B; RYR3; GRIN2C; KCNJ9; GNB1; GNG11; CALM3; KCNJ5; Adcy4
    Retrograde endocannabinoid signaling GABRA1; MAPK8; GNB1; PRKACG; GNAQ; GABRA2; Adcy4; PRKCA; GABRA5; SLC17A8
    Glutamatergic synapse GNG11; GNAO1; SLC1A1; GNAI3; GNG13; GNG12; GRM6; GRM5; SLC1A6; GRIN2B
    Cholinergic synapse CHRM4; PIK3CD; GNAI1; MAPK1; PRKCA; GNB4; CAMK2G; CREB3L1; GNG10; ACHE
    Serotonergic synapse ALOX12B; ALOX12; CYP2C55; ALOX12E; GNG2; PLA2G4A; HTR1B; NRAS; GNG12; GNG11
    GABAergic synapse PRKACA; GNG13; GNG2; GNG7; GNG4; SLC38A2; SRC; GNB1; GNGT1; SLC38A3
    Dopaminergic synapse PPP2CB; GNG3; CALM3; DRD3; PRKACB; AKT2; GRIN2B; SCN1A; PLCB1; GNGT2
    Morphine addiction GABRG3; GABBR1; PDE10A; PDE4C; GNG12; PRKCA; GNG8; GABRA6; PDE4A; GNAS
    Pathways in cancer TPM3; GNG13; CDH1; GNAI2; FIGF; LAMA4; CCDC6; CSF3R; GNB3; FZD3

    GNG4 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by GNG4 itself. We selected most functions GNG4 had, and list some proteins which have the same functions with GNG4. You can find most of the proteins on our site.

    Function Related Protein
    protein binding CD86; ARFIP2; IFI6; PTCRA; SYNE3; DNASE1; DNAJB2; VSIG4; SH3BP1; EIF3E
    signal transducer activity TAS2R118; CD40; VMN1R46; GRM8B; FZD1; VMN1R48; GNAL; TAS2R140; TAS2R110; OLFR50

    GNG4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNG4 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNG4.


    Padigel, UM; Stein, L; et al. Signaling through G alpha i2 protein is required for recruitment of neutrophils for antibody-mediated elimination of larval Strongyloides stercoralis in mice. JOURNAL OF LEUKOCYTE BIOLOGY 81:1120-1126(2007).
    Fabbri, E; Selva, C; et al. Identification and properties of a Gs protein in catfish liver membranes. GENERAL AND COMPARATIVE ENDOCRINOLOGY 125:340-348(2002).

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