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GPR132

Official Full Name

G protein-coupled receptor 132
Overview

This gene encodes a subfamily member of the G-protein couple receptor (GPCR) superfamily. The encoded protein is a high-affinity receptor for lysophosphatidylcholine (LPC), a major phospholipid component of oxidized low density lipoprotein. This protein may react to LPC levels at sites of inflammation to limit the expansion of tissue-infiltrating cells. A similar protein in mouse is involved in cell cycle progression.
Synonyms

GPR132; G protein-coupled receptor 132; probable G-protein coupled receptor 132; G2 accumulation; G2A; G2 accumulation protein; G protein-coupled receptor G2A; MGC99642;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads
Assay Kits

Species

Homo sapiens (Human)
Human
Mouse

Source

E.coli expression system
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GPR132-5181H	Recombinant Human GPR132 Protein	Wheat Germ	N/A		Inquiry
Human	GPR132-183H	Recombinant Human GPR132 Full Length Transmembrane protein(Nanodisc)	HEK293	N/A		Inquiry
Human	GPR132-5621HF	Recombinant Full Length Human GPR132 Protein	In Vitro Cell Free System		221 amino acids	Inquiry
Human	GPR132-5182H	Recombinant Human GPR132 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Mouse	GPR132-7139M	Recombinant Mouse GPR132 Protein	Mammalian Cell	His		Inquiry
Mouse	GPR132-3848M	Recombinant Mouse GPR132 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	GPR132-3848M-B	Recombinant Mouse GPR132 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Homo sapiens (Human)	RFL36621HF	Recombinant Full Length Human Probable G-Protein Coupled Receptor 132(Gpr132) Protein, His-Tagged	E.coli expression system	His	Full Length (1-380)	Inquiry
	Kit-1281	GPR132 CHO-K1 β-Arrestin Orphan GPCR Assay Kit		N/A		Inquiry

Involved Pathway
Protein Function
Interacting Protein
GPR132 Related Articles

GPR132 involved in several pathways and played different roles in them. We selected most pathways GPR132 participated on our site, such as Class A/1 (Rhodopsin-like receptors), G alpha (q) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR132 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Class A/1 (Rhodopsin-like receptors)	RLN3A;GPR18;PENKB;ZFPM2B;ADORA1;OPN1LW2;FPR-RS4;PROKR1A;OPN1MW2
G alpha (q) signalling events	QRFPR;EDNRAB;PROK2;NMU;LPAR2A;EDN2;GCGB;ARHGEF25;NMBA
GPCR downstream signaling	OXGR1A.1;RGS10;OPN1SW;SST1.1;DRD3;FPR-RS6;RGS18;CRH;PDE10A
GPCR ligand binding	RGS1;NPFF;GPR37L1;CNR2;FZD10;GPR132B;HEBP1;PTGDR2;PPY
GPCRs, Other	VN1R1;VMN1R48;VMN1R52;LGR6;VMN1R49;SETD6;GPR56;GPR77;EMR3
Gastrin-CREB signalling pathway via PKC and MAPK	NMUR1;RGS18;LPAR5A;ARHGEF25;TRH;PRKCHB;NMB;RGS21;DGKB
Non-odorant GPCRs	CELSR3;OPN3;GPR132;CELSR1;EMR4;O3far1;BAI2;RRH;GPR15
Signal Transduction	ARHGAP19;SDR9C7;METAP1;RGS12;LGR6;ADH8A;RHOT1B;TLE3;CGNB

GPR132 has several biochemical functions, for example, G-protein coupled receptor activity, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR132 itself. We selected most functions GPR132 had, and list some proteins which have the same functions with GPR132. You can find most of the proteins on our site.

Function	Related Protein
G-protein coupled receptor activity	LPAR5A;GPR173;GPR116;FZD9;DRD2L;OPRD1A;COR6;OLFR477;NMUR1
signal transducer activity	GPR184;GNA14;IL11RA;OLFR78;OLFR469;PLEKHB1;VOPP1;TAS2R114;S1PR3A

GPR132 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR132 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR132.

Yin, J; Yu, FSX; et al. ERK1/2 Mediate Wounding- and G-protein-Coupled Receptor Ligands-Induced EGFR Activation via Regulating ADAM17 and HB-EGF Shedding. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 50:132-139(2009).

Cook, LB; Zhu, CC; et al. Thyrotropin-releasing hormone receptor processing: Role of ubiquitination and proteasomal degradation. MOLECULAR ENDOCRINOLOGY 17:1777-1791(2003).

Chandrasekar, B; Mummidi, S; et al. Fractalkine (CX3CL1) stimulated by nuclear factor kappa B (NF-kappa B)-dependent inflammatory signals induces aortic smooth muscle cell proliferation through an autocrine pathway. BIOCHEMICAL JOURNAL 373:547-558(2003).

Mace, G; Jaume, M; et al. Identification of mu-opioid receptor epitopes recognized by agonistic IgG. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 280:1142-1147(2001).