|Official Full Name||G protein-coupled receptor 161|
|Background||Upon ligand binding, G protein-coupled receptors, such as GPR161, activate cytoplasmic G proteins (see GNAS, MIM;139320), allowing the receptors to transduce extracellular signals across the plasma membrane into the cell.;Phosphorylation of the receptor attenuates signaling (Matteson et al., 2008 (PubMed 18250320)).|
|Synonyms||GPR161; G protein-coupled receptor 161; G-protein coupled receptor 161; RE2; G protein coupled receptor 161; G protein coupled receptor RE2; OTTHUMP00000032586; OTTHUMP00000032587; G-protein coupled receptor RE2|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
GPR161 involved in several pathways and played different roles in them. We selected most pathways GPR161 participated on our site, such as Hedgehog off state, Hedgehog on state, Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR161 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Hedgehog off state||TULP3; IFT172; IFT52; TTC21B; GPR161; INTU; OFD1; BBS13; WDR35; KIF3A|
|Hedgehog on state||EFCAB7; KIF3A; GPR161; SPOP; KIF7; EVC2; CDON; EVC; RPGRIP1L; MKS1|
|Signal Transduction||NOG; HHAT; RTKN; OTULINB; ARHGAP10; TMED5; PNOCB; EFCAB7; SDR9C7; GPR37L1|
|Signaling by Hedgehog||BOC; IFT52; WDR19; SCUBE2; DISP2; SPOP; NOTUM; RPGRIP1L; MKS1; GAS8|
GPR161 has several biochemical functions, for example, G-protein coupled amine receptor activity, G-protein coupled receptor activity, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR161 itself. We selected most functions GPR161 had, and list some proteins which have the same functions with GPR161. You can find most of the proteins on our site.
|G-protein coupled amine receptor activity||TAAR8A; DRD3; DRD4-RS; TAAR8C; DRD5; TAAR7F; TAAR7B; TAAR2; GPR161; GPR21|
|G-protein coupled receptor activity||OR4F29; EDNRAA; GPR31; TAAR7F; OLFR147; RHO; OLFR502; TAAR12B; CHRM5A; FPR2|
|signal transducer activity||GNG2; MAPKAPK2; GNB1; NPFFR1L1; TACR3A; GNA15; TAS2R117; CANT1; VMN2R116; OPN3|
GPR161 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR161 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR161.