• Official Full Name
  • G protein-coupled receptor 27
  • Background
  • GPR27 is a member of the G protein-coupled receptors (GPCRs), a large family of receptors that have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli such as neurotransmitters, hormones, or light induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins.[supplied by OMIM, May 2010]
  • Synonyms
  • GPR27; G protein-coupled receptor 27; SREB1; probable G-protein coupled receptor 27; super conserved receptor expressed in brain 1;
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GPR27 Protein
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GPR27 Protein
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat GPR27 Protein
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GPR27
Source (Host):Species:
Product nameGPR27 CHO-K1 β-Arrestin Orphan GPCR Assay Kit

Involved Pathway

GPR27 involved in several pathways and played different roles in them. We selected most pathways GPR27 participated on our site, such as GPCRs, Class A Rhodopsin-like, Odorant GPCRs, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR27 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
GPCRs, Class A Rhodopsin-like
CX3CR1; FPR-RS3; SSTR3; GPR39; GPR18; GPR63; DRD4; GPR37L1; GPR17; SSTR2
Odorant GPCRs

Protein Function

GPR27 has several biochemical functions, for example, G-protein coupled receptor activity, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR27 itself. We selected most functions GPR27 had, and list some proteins which have the same functions with GPR27. You can find most of the proteins on our site.
Related Protein
Function G-protein coupled receptor activity
Related Protein NMUR1; OLFR13; AGTR1A; NPY; GPR75; ADRB3A; OR3A2; TAS2R103; FPR-RS3; OXGR1A.1
Function signal transducer activity
Related Protein IL15RA; TAAR14D; OLFR49; OPN1LW2; MTNR1C; UNC13B; CNOT7; GPR186; OLFCG5; GNB3

GPR27 Related Articles

Petrich, A; Mann, A; et al. Phosphorylation of Threonine 333 Regulates Trafficking of the Human sst(5) Somatostatin Receptor. MOLECULAR ENDOCRINOLOGY 27:671-682(2013).
Pierce, M; Sandrock, R; et al. Measurement of thyroid stimulating immunoglobulins using a novel thyroid stimulating hormone receptor-guanine nucleotide-binding protein, (GNAS) fusion bioassay. CLINICAL AND EXPERIMENTAL IMMUNOLOGY 170:115-121(2012).