gprc6a
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  • Official Full Name
  • G protein-coupled receptor, family C, group 6, member A
  • Background
  • G protein-coupled receptor family C group 6 member A is a protein that in humans is encoded by the GPRC6A gene. This receptor functions as a sensor of L-amino acids, calcium, osteocalcin, and steroids.
  • Synonyms
  • GPRC6A; G protein-coupled receptor, family C, group 6, member A; G-protein coupled receptor family C group 6 member A; bA86F4.3; hGPCR33; hGPRC6A; predicted with SOSUI analysis; G-protein coupled receptor GPCR33; seven transmembrane helix receptor; GPCR
Cat.#:GPRC6A-1193HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human GPRC6A
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Cat.#:GPRC6A-2673RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat GPRC6A Protein
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Cat.#:GPRC6A-1941ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GPRC6A
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Cat.#:GPRC6A-5769HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human GPRC6A 293 Cell Lysate
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Involved Pathway

GPRC6A involved in several pathways and played different roles in them. We selected most pathways GPRC6A participated on our site, such as Class C/3 (Metabotropic glutamate/pheromone receptors), G alpha (q) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPRC6A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Class C/3 (Metabotropic glutamate/pheromone receptors)
CASR; TAS2R13; TAS2R7; TAS2R16; TAS2R3; GPRC6A
G alpha (q) signalling events
OPN4; GPRC6A; HCRT; AGTR1; ABHD12; TRIO; FPR-RS4; GPR132B; TAE1; GPR132
GPCR downstream signaling
ITSN1; AGT; CRHB; RGS11; NMBA; GPBAR1; RGR; OXGR1A.1; APLNR; TAS2R13
GPCR ligand binding
SSTR1; GRP; RHOL; CRHB; OPN5; GNB5A; ADORA2A; FPR-RS6; CCL35.1; EDN1
Gastrin-CREB signalling pathway via PKC and MAPK
GPR132; QRFP; ANXA1C; GPR65; KISS1; PROKR2; FPR-RS3; OPN4.1; TRPC3; NMU
Signal Transduction
RBP2A; ARHGAP4; ARHGAP19; FSTL1B; RLN1; SDR9C7; GPR177; CDC42EP2; APOC2; GHRB
Signaling by GPCR
OXGR1A.3; EMR2; SST1.1; GPR120; ADCYAP1B; GPR39; HEBP1; ARHGEF1B; GPR31B; GPR31

Protein Function

GPRC6A has several biochemical functions, for example, G-protein coupled receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPRC6A itself. We selected most functions GPRC6A had, and list some proteins which have the same functions with GPRC6A. You can find most of the proteins on our site.
Function
Related Protein
Function G-protein coupled receptor activity
Related Protein EMR2; GPR183A; TAS2R110; GPRC5B; GRM5; TAAR1B; LPAR6A; FZD3B; OXGR1A.1; GHSRA

GPRC6A Related Articles

De Toni, L; De Filippis, V; et al. Uncarboxylated Osteocalcin Stimulates 25-Hydroxy Vitamin D Production in Leydig Cell Line Through a GPRC6a-Dependent Pathway. ENDOCRINOLOGY 155:4266-4274(2014).
Harno, E; Edwards, G; et al. Evidence for the presence of GPRC6A receptors in rat mesenteric arteries. CELL CALCIUM 44:210-219(2008).