gsta5
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  • Official Full Name
  • glutathione S-transferase alpha 5
  • Background
  • The glutathione S-transferases (GST; EC 2.5.1.18) catalyze the conjugation of reduced glutathiones and a variety of electrophiles, including many known carcinogens and mutagens. The cytosolic GSTs belong to a large superfamily, with members located on different chromosomes. For additional information on GSTs, see GSTA1 (MIM 138359).
  • Synonyms
  • GSTA5; glutathione S-transferase alpha 5; glutathione S transferase A5; glutathione S-transferase A5; glutathione S transferase alpha 5; glutathione S transferase Yc 2; Glutathione S-transferase A5-5; GST A5 5; GST class-alpha member 5; GST Yc2; Gsta5 glutathione S transferase Yc2 subunit; GSTA5_HUMAN; glutathione transferase A5
Cat.#:GSTA5-4412HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GSTA5 Protein, GST-tagged
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Cat.#:GSTA5-849HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human GSTA5
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Cat.#:Gsta5-2014RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Gsta5 protein, His-tagged
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Cat.#:GSTA5-573CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus GSTA5 Protein, His-tagged
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Cat.#:GSTA5-5716HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human GSTA5 293 Cell Lysate
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Involved Pathway

GSTA5 involved in several pathways and played different roles in them. We selected most pathways GSTA5 participated on our site, such as Glutathione metabolism, Metabolism of xenobiotics by cytochrome P, Drug metabolism - cytochrome P, which may be useful for your reference. Also, other proteins which involved in the same pathway with GSTA5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glutathione metabolism
GGT6; GPX4A; MGST1; MGST2; GSTM7; GSTT2B; GSTM2; IDH2; OPLAH; GSTM6
Metabolism of xenobiotics by cytochrome P
DHDH; MGST1.2; UGT2B15; UGT1A6; UGT1A7; ALDH1A3; UGT1AB; GSTM3; MGST1; UGT1A2
Drug metabolism - cytochrome P
AOX2P; ALDH3B1; GSTA1; UGT2A1; GSTA5; MGST1.1; GSTM1; GSTA3; GSTA2; GSTP2
Chemical carcinogenesis
GSTA3; CCBL2; ALDH3B2; GSTT2B; CYP2A13; GSTP1; ADH1; UGT1A6A; UGT2B7; UGT1A6B

Protein Function

GSTA5 has several biochemical functions, for example, glutathione transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GSTA5 itself. We selected most functions GSTA5 had, and list some proteins which have the same functions with GSTA5. You can find most of the proteins on our site.
Function
Related Protein
Function glutathione transferase activity
Related Protein EEF1E1; GSTM3; GSTM4; GSTT2; GSTM5; GDAP1; GDAP1L1; HPGDS; EEF1G; GSTM2

GSTA5 Related Articles

Miao, WM; Hu, LG; et al. Oltipraz is a bifunctional inducer activating both phase I and phase II drug-metabolizing enzymes via the xenobiotic responsive element. MOLECULAR PHARMACOLOGY 64:346-354(2003).
Staffas, L; Ellis, EM; et al. Growth hormone- and testosterone-dependent regulation of glutathione transferase subunit A5 in rat liver. BIOCHEMICAL JOURNAL 332:763-768(1998).