gtf2e2
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  • Official Full Name
  • GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa
  • Background
  • The human Transcription Factor IIE (TFIIE) is composed of 56 kDa (alpha) and 34 kDa (beta) subunits and is shown to be a heterotetramer. The 56 kDa subunit contains a region similar to a zinc-binding domain and a region sharing homology with the catalytic loop of a kinase domain. TFIIE binds to RNA polymerase II in solution and joins the preinitiation complex probably concomitant with RNA polymerase II and TFIIF. alpha-TFIIE beta is an af?nity-puri?ed rabbit polyclonal antibody raised against a recombinant full-length p34 subunit of the TFIIE complex.
  • Synonyms
  • GTF2E2; general transcription factor IIE, polypeptide 2, beta 34kDa; general transcription factor IIE, polypeptide 2 (beta subunit, 34kD); transcription initiation factor IIE subunit beta; FE; TF2E2; TFIIE B; TFIIE-beta; general transcription factor IIE subunit 2; TFIIE-B;
Cat.#:GTF2E2-4443HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GTF2E2 Protein, GST-tagged
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Cat.#:GTF2E2-1182HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GTF2E2
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Cat.#:GTF2E2-30319THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GTF2E2, His-tagged
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Cat.#:GTF2E2-8456HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GTF2E2, His-tagged
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Cat.#:GTF2E2-2004RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey GTF2E2 Protein, His-tagged
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Cat.#:GTF2E2-2103CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken GTF2E2
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Cat.#:GTF2E2-12003ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GTF2E2
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Cat.#:GTF2E2-466HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human General Transcription Factor IIE, Polypeptide 2, Beta 34kDa, His-tagged
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Cat.#:GTF2E2-5701HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GTF2E2 293 Cell Lysate
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Involved Pathway

GTF2E2 involved in several pathways and played different roles in them. We selected most pathways GTF2E2 participated on our site, such as Basal transcription factors, Epstein-Barr virus infection, Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF2E2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Basal transcription factors
TAF6L; CCNH; ERCC3; GTF2H5; ERCC2; TAF4B; TBPL2; GTF2H3-2; TAF7L; TAF1
Epstein-Barr virus infection
AKT1; POLR3H; POLR1D; POLR2C; MAPK9; HLA-DQA1; STAT3; PIK3R1; HLA-DPB1; HSPA1A
Viral carcinogenesis
GTF2H2C; TBPL1; HNRNPK; SND1; HDAC2; HIST1H4B; HIST1H2BQ; PIK3R1; TRAF3; HIST1H2BE

Protein Function

GTF2E2 has several biochemical functions, for example, DNA binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF2E2 itself. We selected most functions GTF2E2 had, and list some proteins which have the same functions with GTF2E2. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein TIGD3; POLE2; POU2AF1; SOX3; MBD1; RPP21; HOXB1; KDM5C; ZNF287; KDM5BA
Function poly(A) RNA binding
Related Protein HIST1H4J; HIST1H4N; MRPS30; FRG1; YTHDF1; LARP7; C2orf15; HLA-A; MRPL37; HHATL
Function protein binding
Related Protein ARFGAP1; SIX5; TBC1D1; PKD2; NCAPH; C16orf87; FRMPD2; POT1A; WDFY2; SNRPB2

Interacting Protein

GTF2E2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF2E2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF2E2.
GTF2E1; MCC; pst; ssdna_dtdg