gtf2h2c
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  • Official Full Name
  • GTF2H2C general transcription factor IIH, polypeptide 2C [ Homo sapiens ]
  • Background
  • This gene encodes a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). In brain studies, the encoded protein was found with the GRIP/AMPA receptor complex. Multiple alternatively spliced transcript variants have been described that encode different protein isoforms; however, the full-length nature and biological validity of all of these variants have not been determined.
  • Synonyms
  • general transcription factor IIH, polypeptide 2C; 31394; Ensembl:ENSG00000183474; FLJ77682, MGC102806, MGC198575, DKFZp686P18101; general transcription factor IIH subunit 2-like protein; general transcription factor IIH polypeptide 2-like protein
Cat.#:GTF2H2C-2458HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human GTF2H2C Protein, MYC/DDK-tagged
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Cat.#:GTF2H2C-13597HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GTF2H2C, GST-tagged
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Involved Pathway

GTF2H2C involved in several pathways and played different roles in them. We selected most pathways GTF2H2C participated on our site, such as Basal transcription factors, Nucleotide excision repair, Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF2H2C were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Basal transcription factors
TAF6; TAF10; TAF11; GTF2H1; ERCC2; TAF13; TAF12; GTF2E1; GTF2B; TAF5L
Nucleotide excision repair
RPA1; RAD23AA; GTF2H3-2; GTF2H5; COPS6; XPC; CUL4A; BIVM-ERCC5; COPS8; YY1
Viral carcinogenesis
HIST1H2BF; PIK3R1; TRP53; HIST2H2BE; HIST1H2BG; HDAC11; TTC6; PRKACB; HIST1H2BI; TP53

Protein Function

GTF2H2C has several biochemical functions, for example, protein binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF2H2C itself. We selected most functions GTF2H2C had, and list some proteins which have the same functions with GTF2H2C. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein HUWE1; MED25; ACVR1; TMEM182; KIAA1609; COPS4; BAG5; DNM1; RPS10; ATL2
Function zinc ion binding
Related Protein ZDHHC21; ZNF330; TNKS; MDM2; TIMM10; FTR72; APOBEC2A; MMP23B; MIB1; ZNF385A

Interacting Protein

GTF2H2C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF2H2C here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF2H2C.
ERCC2; GTF2H3; DZIP3; SUV39H1