gtf3a
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  • Official Full Name
  • general transcription factor IIIA
  • Background
  • The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq, Jul 2008]
  • Synonyms
  • GTF3A; general transcription factor IIIA; AP2; TFIIIA; transcription factor IIIA;
Cat.#:GTF3A-4461HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GTF3A Protein, GST-tagged
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Cat.#:GTF3A-1057HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GTF3A protein, His & T7-tagged
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Cat.#:GTF3A-7366MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GTF3A Protein
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Cat.#:Gtf3a-1681RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Gtf3a protein, His & T7-tagged
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Cat.#:GTF3A-2746RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat GTF3A Protein
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Cat.#:GTF3A-3806CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken GTF3A
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Involved Pathway

GTF3A involved in several pathways and played different roles in them. We selected most pathways GTF3A participated on our site, such as Gene Expression, RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription, RNA Polymerase III Transcription, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF3A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Gene Expression
ZIM2; ZFP473; ZNF691; Txn1; MED25; ZNF701; COX6C; ZNF302; ZNF266; CRCP
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
SNAPC1A; GTF3A; MTERF; ZNF143; GTF3C3; SNAPC3; ZFP143; PTRF; MBD3A; MBD3B
RNA Polymerase III Transcription
ZFP143; ZNF143B; POLR3GLA; NFIA; SNAPC1A; NFIB; SNAPC1B; GTF3C3; GTF3AB; BRF1B
RNA Polymerase III Transcription Initiation
GTF3C3; GTF3AA; POLR3GLA; GTF3C5; SNAPC3; ZNF143A; BRF1; ZFP143; GTF3C4; BRF2
RNA Polymerase III Transcription Initiation From Type 1 Promoter
BRF1B; POLR3GLA; GTF3A; GTF3C2; GTF3C5; GTF3C3; GTF3AA; GTF3AB; BRF1; GTF3C4

Protein Function

GTF3A has several biochemical functions, for example, DNA binding, RNA binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF3A itself. We selected most functions GTF3A had, and list some proteins which have the same functions with GTF3A. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein EVE1; HIST1H2AG; ZNF319; POLR1D; SP6; KIF22; POLR2L; DHARMA; ZNF358; CRY2
Function RNA binding
Related Protein RNASEL; EIF2C3; RNMT; RPS14; RANBP2; ARHGEF28; ADARB2; CLUHA; DNMT1; MSI1
Function metal ion binding
Related Protein THAP4; LIMS2; MGRN1B; ZNF45; NDUFS7; BA1; ZNF620; CENPT; NUDT13; ATP2A1L
Function nucleic acid binding
Related Protein ZFP827; ANG4; ZFP536; ZBTB12.2; FAM90A1; RNASE11; RBPMS2A; SFRS3B; ZNRD1; MSI2B
Function transcription factor activity, sequence-specific DNA binding
Related Protein POU3F1; SHOX; MLXIPL; GLI4; CEBP1; ARNTL2; SOX32; FOXI1; NFE2L3; NR1I3