|Official Full Name||general transcription factor IIIA|
|Background||The product of this gene is a zinc finger protein with nine Cis-His zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq, Jul 2008]|
|Synonyms||GTF3A; general transcription factor IIIA; AP2; TFIIIA; transcription factor IIIA;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
GTF3A involved in several pathways and played different roles in them. We selected most pathways GTF3A participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF3A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Gene Expression||SCO1; NR2C2AP; PAIP1; PHF1; TEAD1A; ZNF658; RORAA; ZNF79; SNAPC1A; ZNF750|
|RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription||NFIA; BRF2; CBX3A; SNAPC1; CBX3; GATAD2A; POLR3GLA; PTRFB; RRN3; BRF1|
|RNA Polymerase III Transcription||ZNF143B; SNAPC1; GTF3C5; BRF2; SNAPC2; GTF3AA; GTF3A; GTF3C4; SNAPC5; POU2F1B|
|RNA Polymerase III Transcription Initiation||SNAPC1; GTF3C2; SNAPC5; BRF2; BRF1B; POLR3GLA; GTF3AB; SNAPC1B; GTF3C4; SNAPC4|
|RNA Polymerase III Transcription Initiation From Type 1 Promoter||BRF1B; GTF3AA; GTF3A; POLR3GLA; BRF1; GTF3C2; GTF3AB; GTF3C4; GTF3C3; GTF3C5|
GTF3A has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF3A itself. We selected most functions GTF3A had, and list some proteins which have the same functions with GTF3A. You can find most of the proteins on our site.
|DNA binding||PA2G4; MCM3L; CREM; POLR2B; MB21D1; ZFP28; JRK; TOX2; ZFP689; FUS|
|RNA binding||CNOT8; RPL19; RPL29; HNRNPA0; DNMT1; SMN2; PDCD4; APOBEC3G; NOP56; CPSF1|
|metal ion binding||EFCAB5; EXT1C; CSH2; FRAS1; ZNF428; GMEB2; PDE1B; ZFP652; PARP12B; STK32C|
|nucleic acid binding||ZNF728; PRDM12; BAT1; ZIC2B; PPRC1; ZNF878; HNRNPL2; PRDM8B; ANG4; RSFR|
|transcription factor activity, sequence-specific DNA binding||ZHX1; ZNF74; PPARD; Trl; STAT1B; ALX3; SCAND3; ETS1; DMRTA2; MLXIPL|
GTF3A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF3A here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF3A.