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Official Full Name general transcription factor IIIA
Background The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq, Jul 2008]
Synonyms GTF3A; general transcription factor IIIA; AP2; TFIIIA; transcription factor IIIA;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GTF3A-1057H Recombinant Human GTF3A protein, His & T7-tagged E.coli His/T7
    Human GTF3A-4461H Recombinant Human GTF3A Protein, GST-tagged Wheat Germ GST
    Mouse GTF3A-7366M Recombinant Mouse GTF3A Protein Mammalian Cell His
    Rat Gtf3a-1681R Recombinant Rat Gtf3a protein, His & T7-tagged E.coli His/T7
    Rat GTF3A-2746R Recombinant Rat GTF3A Protein Mammalian Cell His
    Chicken GTF3A-3806C Recombinant Chicken GTF3A Mammalian Cell His

    GTF3A involved in several pathways and played different roles in them. We selected most pathways GTF3A participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF3A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Gene Expression SCO1; NR2C2AP; PAIP1; PHF1; TEAD1A; ZNF658; RORAA; ZNF79; SNAPC1A; ZNF750
    RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription NFIA; BRF2; CBX3A; SNAPC1; CBX3; GATAD2A; POLR3GLA; PTRFB; RRN3; BRF1
    RNA Polymerase III Transcription ZNF143B; SNAPC1; GTF3C5; BRF2; SNAPC2; GTF3AA; GTF3A; GTF3C4; SNAPC5; POU2F1B
    RNA Polymerase III Transcription Initiation SNAPC1; GTF3C2; SNAPC5; BRF2; BRF1B; POLR3GLA; GTF3AB; SNAPC1B; GTF3C4; SNAPC4
    RNA Polymerase III Transcription Initiation From Type 1 Promoter BRF1B; GTF3AA; GTF3A; POLR3GLA; BRF1; GTF3C2; GTF3AB; GTF3C4; GTF3C3; GTF3C5

    GTF3A has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF3A itself. We selected most functions GTF3A had, and list some proteins which have the same functions with GTF3A. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding PA2G4; MCM3L; CREM; POLR2B; MB21D1; ZFP28; JRK; TOX2; ZFP689; FUS
    RNA binding CNOT8; RPL19; RPL29; HNRNPA0; DNMT1; SMN2; PDCD4; APOBEC3G; NOP56; CPSF1
    metal ion binding EFCAB5; EXT1C; CSH2; FRAS1; ZNF428; GMEB2; PDE1B; ZFP652; PARP12B; STK32C
    nucleic acid binding ZNF728; PRDM12; BAT1; ZIC2B; PPRC1; ZNF878; HNRNPL2; PRDM8B; ANG4; RSFR
    transcription factor activity, sequence-specific DNA binding ZHX1; ZNF74; PPARD; Trl; STAT1B; ALX3; SCAND3; ETS1; DMRTA2; MLXIPL

    GTF3A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF3A here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF3A.

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