h3f3c
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  • Official Full Name
  • H3 histone, family 3C
  • Background
  • Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Hominid-specific H3.5/H3F3C preferentially colocalizes with euchromatin, and it is associated with actively transcribed genes.
  • Synonyms
  • H3F3C; H3 histone, family 3C; histone H3.3C; H3.5; histone variant H3.5;
Cat.#:H3F3C-3129CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken H3F3C
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Cat.#:H3F3C-10364ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish H3F3C
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Cat.#:H3F3C-5652HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human H3F3C 293 Cell Lysate
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Involved Pathway

H3F3C involved in several pathways and played different roles in them. We selected most pathways H3F3C participated on our site, such as Alcoholism, Transcriptional misregulation in cancer, Systemic lupus erythematosus, which may be useful for your reference. Also, other proteins which involved in the same pathway with H3F3C were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Alcoholism
HIST1H4E; CALM3; HIST2H4; BDNF; MAOA; DRD1A; ATF4; NPY; HDAC10; HDAC1
Transcriptional misregulation in cancer
ID2; MLLT3; MMP3; RXRA; PDGFA; ELANE; NTRK1; CD14; FCGR1A; CLSTN2
Systemic lupus erythematosus
FCGR2A; HIST1H2AO; HIST1H2BE; HIST1H2BJ; GRIN2A; HIST1H2BG; FCGR1A; H3F3C; IFNG; C8A

Protein Function

H3F3C has several biochemical functions, for example, nucleosomal DNA binding, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by H3F3C itself. We selected most functions H3F3C had, and list some proteins which have the same functions with H3F3C. You can find most of the proteins on our site.
Function
Related Protein
Function nucleosomal DNA binding
Related Protein H2AFY; HMGN3; H3F3A; NSBP1; H3F3B; H3F3C; RCC1; HMGN5; HMGN2; H1FOO
Function protein binding
Related Protein NOS1; FBXO17; TBC1D17; NIPAL3; CDK10; NOP58; ZNF559-ZNF177; ZFPM1; SUPV3L1; GTF2E1
Function protein heterodimerization activity
Related Protein RXRA; UGT1A2; Defa-rs7; H2AFZ; ZBTB1; GTF2A1; CHRNB2; NPAS4; KCNB2; CUL3

Interacting Protein

H3F3C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with H3F3C here. Most of them are supplied by our site. Hope this information will be useful for your research of H3F3C.
NASP; PRMT5; SUV39H1; KDM1A; KDM4B; SETMAR; q8cla8_yerpe; SMYD1; PRMT6; WHSC1L1; SMYD3; PRMT7; VP24; VP24